Bauer B, Majic M, Rauthe S, Bröcker E-B, Kerstan A
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinkum Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Deutschland.
Unfallchirurg. 2012 Dec;115(12):1116-9. doi: 10.1007/s00113-011-2116-5.
We report the case of a long-lasting cutaneous side effect after inappropriate use of Octenisept® solution (containing octenidine and phenoxyethanol). Following lavage of an abscess in the inguinal region, a painful erythematous induration mimicking cellulitis persisted for several months. Manual lymphatic drainage considerably improved the symptoms. Octenisept® shows considerable tissue toxicity in vivo including - but not restricted to - blood vessel damage. Deterioration of endothelial cells followed by oedema and continued tissue damage can be seen histologically. Despite the fact that there is a circular letter issued by the manufacturer as well as a boxed warning on the bottles, the awareness to avoid this misuse of Octenisept® is still lacking.
