在纳米尺度下可视化液体中的病毒颗粒移动性。
Visualizing virus particle mobility in liquid at the nanoscale.
作者信息
Cameron Varano A, Rahimi Amina, Dukes Madeline J, Poelzing Steven, M McDonald Sarah, Kelly Deborah F
机构信息
Virginia Tech Carilion Research Institute, Roanoke, VA 24016, USA.
Application Science, Protochips, Inc., Raleigh, NC 27606, USA.
出版信息
Chem Commun (Camb). 2015 Nov 21;51(90):16176-9. doi: 10.1039/c5cc05744b.
Abstract
Currently, there remains a critical need to develop real-time imaging resources for life sciences. Here, we demonstrate the use of high resolution in situ imaging to observe biological complexes in liquid at the nanoscale. Using a model virus system, we produced the first time-resolved videos of individual biological complexes moving in solution within an electron microscope.
摘要
目前，生命科学领域仍迫切需要开发实时成像资源。在此，我们展示了利用高分辨率原位成像在纳米尺度观察液体中的生物复合物。使用一个模型病毒系统，我们首次在电子显微镜下制作了单个生物复合物在溶液中移动的时间分辨视频。
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