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诊断试验准确性:系统评价与Meta分析方法

Diagnostic test accuracy: methods for systematic review and meta-analysis.

作者信息

Campbell Jared M, Klugar Miloslav, Ding Sandrine, Carmody Dennis P, Hakonsen Sasja J, Jadotte Yuri T, White Sarahlouise, Munn Zachary

机构信息

1The Joanna Briggs Institute, Faculty of Health Sciences, University of Adelaide, Adelaide, Australia 2Department of Social Medicine and Public Health, Faculty of Medicine and Dentistry, The Czech Republic (Middle European) Centre for Evidence-Based Health Care: An Affiliated Centre of The Joanna Briggs Institute, Palacky University Olomouc, Olomouc, Czech Republic 3Bureau d'Echanges des Savoirs Pour des praTiques Exemplaires de Soins (BEST): An Affiliate Centre of The Joanna Briggs Institute, Lausanne, Switzerland 4Rutgers Robert Wood Johnson Medical School, Institute for the Study of Child Development, New Brunswick, New Jersey, USA 5Center for Kliniske Retningslinjer, Institut for Medicin and Sundhedsteknologi, Aalborg Universitet, Aalborg, Denmark 6Northeast Institute for Evidence Synthesis and Translation, A Collaborating Center of the Joanna Briggs Institute, Division of Nursing Science, Rutgers School of Nursing 7Department of Quantitative Methods, Biostatistics and Epidemiology, Rutgers School of Public Health, Newark, New Jersey, USA 8Department of Speech Pathology and Audiology, Flinders University, Adelaide, Australia.

出版信息

Int J Evid Based Healthc. 2015 Sep;13(3):154-62. doi: 10.1097/XEB.0000000000000061.

DOI:10.1097/XEB.0000000000000061
PMID:26355602
Abstract

Systematic reviews are carried out to provide an answer to a clinical question based on all available evidence (published and unpublished), to critically appraise the quality of studies, and account for and explain variations between the results of studies. The Joanna Briggs Institute specializes in providing methodological guidance for the conduct of systematic reviews and has developed methods and guidance for reviewers conducting systematic reviews of studies of diagnostic test accuracy. Diagnostic tests are used to identify the presence or absence of a condition for the purpose of developing an appropriate treatment plan. Owing to demands for improvements in speed, cost, ease of performance, patient safety, and accuracy, new diagnostic tests are continuously developed, and there are often several tests available for the diagnosis of a particular condition. In order to provide the evidence necessary for clinicians and other healthcare professionals to make informed decisions regarding the optimum test to use, primary studies need to be carried out on the accuracy of diagnostic tests and the results of these studies synthesized through systematic review. The Joanna Briggs Institute and its international collaboration have updated, revised, and developed new guidance for systematic reviews, including systematic reviews of diagnostic test accuracy. This methodological article summarizes that guidance and provides detailed advice on the effective conduct of systematic reviews of diagnostic test accuracy.

摘要

进行系统评价是为了根据所有可得证据(已发表和未发表的)回答临床问题,严格评估研究质量,并解释研究结果之间的差异。乔安娜·布里格斯研究所专门为系统评价的开展提供方法学指导,并为进行诊断试验准确性研究的系统评价的评审人员制定了方法和指南。诊断试验用于确定某种疾病的存在与否,以便制定适当的治疗方案。由于对提高速度、降低成本、操作简便性、患者安全性和准确性的需求,新的诊断试验不断被开发出来,而且通常有几种试验可用于诊断特定疾病。为了提供必要的证据,使临床医生和其他医疗保健专业人员能够就是否使用最佳试验做出明智的决定,需要对诊断试验的准确性进行原始研究,并通过系统评价对这些研究结果进行综合分析。乔安娜·布里格斯研究所及其国际合作团队更新、修订并制定了新的系统评价指南,包括诊断试验准确性的系统评价指南。这篇方法学文章总结了该指南,并就有效开展诊断试验准确性的系统评价提供了详细建议。

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