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美国斑秃的治疗:一项回顾性横断面研究。

Treatment of Alopecia Areata in the United States: A Retrospective Cross-Sectional Study.

作者信息

Farhangian Michael E, McMichael Amy J, Huang Karen E, Feldman Steven R

出版信息

J Drugs Dermatol. 2015 Sep;14(9):1012-4.

Abstract

BACKGROUND

Alopecia Areata (AA) is a non-scarring alopecia that affects millions of Americans, however the way it is treated and which patients seek treatment is not well characterized.

OBJECTIVE

To better understand how AA was being treated in the United States, what type of patients are seen for AA, and what physicians treated them.

METHODS

We analyzed data from the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2001 to 2010. We tabulated patient characteristics, the physicians who treated AA and what treatments were prescribed for AA.

RESULTS

There were an estimated 2.6 million outpatient visits for AA. Patients with AA were most commonly treated by a dermatologists (84.8%). Patients were most commonly treated with topical and injected corticosteroids (61.0%) followed by minoxidil (5.9%) and topical tacrolimus (5.7%). Males made fewer visits per 1,000 capita compared to females (P=0.01).

LIMITATIONS

The NAMCS and NHAMCS do not record severity of disease data.

CONCLUSIONS

Topical and injected corticosteroids are the mainstay of treatment for AA, however the use of steroid sparing agents such as minoxidil is low. Despite no studies demonstrating efficacy, topical tacrolimus was used almost as frequently as minoxidil.

摘要

背景

斑秃(AA)是一种非瘢痕性脱发,影响着数百万美国人,然而其治疗方式以及哪些患者寻求治疗并未得到很好的描述。

目的

为了更好地了解美国斑秃的治疗方式、接受斑秃治疗的患者类型以及治疗他们的医生。

方法

我们分析了2001年至2010年美国国家门诊医疗调查(NAMCS)和国家医院门诊医疗调查(NHAMCS)的数据。我们将患者特征、治疗斑秃的医生以及为斑秃开出的治疗方法制成表格。

结果

估计有260万次斑秃门诊就诊。斑秃患者最常由皮肤科医生治疗(84.8%)。患者最常接受外用和注射皮质类固醇治疗(61.0%),其次是米诺地尔(5.9%)和外用他克莫司(5.7%)。男性每1000人的就诊次数低于女性(P = 0.01)。

局限性

NAMCS和NHAMCS未记录疾病严重程度数据。

结论

外用和注射皮质类固醇是斑秃治疗的主要方法,然而米诺地尔等类固醇节约剂的使用较少。尽管没有研究证明其疗效,但外用他克莫司的使用频率几乎与米诺地尔相同。

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