Department of Dermatology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
J Investig Dermatol Symp Proc. 2020 Nov;20(1):S28-S30. doi: 10.1016/j.jisp.2020.04.004.
The number of alopecia areata (AA) clinical trials with Jak inhibitors of cytoplasmic tyrosine kinases, including Jak1, Jak2, Jak3, and tyrosine-protein kinase has increased significantly since the last Research Summit. This fact means that the conversation about current treatments for AA now also needs to include a discussion of traditionally used off-label therapies as well as evolving therapies as with Jak inhibitors.
自上次研究峰会以来,采用细胞质酪氨酸激酶(包括 Jak1、Jak2、Jak3 和酪氨酸蛋白激酶)Jak 抑制剂的斑秃(AA)临床试验数量显著增加。这一事实意味着,目前关于 AA 的治疗方法的讨论现在还需要包括对传统的非适应证治疗方法以及 Jak 抑制剂等新兴治疗方法的讨论。