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[宫颈残端癌。43例回顾性分析]

[Carcinoma of the cervical stump. Retrospective analysis of 43 cases].

作者信息

Calais G, Leloup R, Chauvet B, Body G, Lansac J, Bougnoux P, Le Floch O

机构信息

Clinique d'oncologie et de radiothérapie, hôpital Bretonneau, CHU, Tours, France.

出版信息

Bull Cancer. 1989;76(10):1103-10.

PMID:2635637
Abstract

Seven to eight percent of cervix carcinomas are carcinomas of the cervical stump. The prognosis for these tumors has sometimes been considered more unfavourable than that for carcinomas on intact uterus. From 1976 to 1986 we treated 43 patients with carcinoma of the cervical stump. The mean age was 63.6 years. Staging system used was FIGO classification modified according to the criteria of Institut Gustave Roussy in Villejuif. There were 12 stage IB, 12 early stage II, 5 late stage II and 14 stage III. Twenty-four centropelvic tumors (IB and early stage II) were treated with radiotherapy and surgery, 2 with surgery alone and one with radiotherapy alone. Late stage II and stage III tumors were treated with radiotherapy alone (+ hysterectomy for two patients). Local control rate was 83% for centropelvic tumors and 53% for late stage II and stage III. Seven patients developed distant metastases. Uncorrected 5-year actuarial survival rate was 78% for centro-pelvic tumors and 46% for late stage II and stage III. Three patients developed severe complications (grade 3). Prognostic factors were: stage, nodal status and pathological status of the cervix after radiotherapy. For the same stage the results were similar to those observed for carcinomas on intact uterus treated at our institution during the same time period.

摘要

7%至8%的宫颈癌为宫颈残端癌。这些肿瘤的预后有时被认为比完整子宫的癌更差。1976年至1986年,我们治疗了43例宫颈残端癌患者。平均年龄为63.6岁。采用的分期系统是根据维勒瑞夫古斯塔夫·鲁西研究所的标准修改后的国际妇产科联盟(FIGO)分类。其中12例为IB期,12例为早期II期,5例为晚期II期,14例为III期。24例中心盆腔肿瘤(IB期和早期II期)接受了放疗和手术治疗,2例仅接受手术治疗,1例仅接受放疗。晚期II期和III期肿瘤仅接受放疗(2例患者加做子宫切除术)。中心盆腔肿瘤的局部控制率为83%,晚期II期和III期为53%。7例患者发生远处转移。中心盆腔肿瘤未经校正的5年精算生存率为78%,晚期II期和III期为46%。3例患者出现严重并发症(3级)。预后因素包括:分期、淋巴结状态以及放疗后宫颈的病理状态。对于相同分期,结果与同期在我们机构治疗的完整子宫癌的观察结果相似。

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