香槟葡萄园工人的职业性呼吸道症状

Work-related respiratory symptoms in Champagne vineyard workers.

作者信息

Perotin J-M, Barbe C, Nguyen K L, Fontaine J-F, Gabignon Y, Nardi J, Launois C, Lebargy F, Lavaud F, Deslee G

机构信息

Department of Respiratory Medicine, University Hospital, 51100 Reims, France. INSERM UMRS 903, University Hospital, 51100, 45 Rue Cognacq Jay, 51100 Reims, France. Phone: +33 32 67 87 614 Fax: +33 32 678 40 30 E-mail:

Clinical Research Unit, University Hospital, 51100 Reims, France.

出版信息

Eur Ann Allergy Clin Immunol. 2015 Sep;47(5):140-4.

PMID:26356997

Abstract

BACKGROUND

Vineyard workers (VW) are exposed to various respiratory allergens. The aims of the study were to determine the prevalence of work related respiratory symptoms (WRS) in Champagne VW in France and to analyze the relationships between symptoms, occupational exposure and sensitization profile.

METHODS

VW of Reims area were prospectively recruited between 2007 and 2010. Demographic and occupational characteristics were recorded. Respiratory symptoms were scored for each month of the past year. Results of respiratory functional tests and skin prick tests for common respiratory allergens, grape moulds and vine pollen were recorded.

RESULTS

307 subjects were included. The prevalence of WRS was 11%. Compared to subjects with symptoms unrelated to work, subjects with WRS were more frequently sensitized to gramineae (34% vs 18%, p = 0.05), described ocular itching (74% vs 37%, p < 0.001) and seasonal symptoms (88% vs 69%, p = 0.03) mainly during lifting and trellising (57% vs 17%, p < 0.001).

CONCLUSION

WRS are frequent in Champagne WV and are associated with a sensitization to gramineae and with activities performed close to vine in late spring.

摘要

背景

葡萄园工人（VW）会接触到各种呼吸道过敏原。本研究的目的是确定法国香槟地区葡萄园工人中与工作相关的呼吸道症状（WRS）的患病率，并分析症状、职业暴露和致敏情况之间的关系。

方法

在2007年至2010年期间前瞻性招募兰斯地区的葡萄园工人。记录人口统计学和职业特征。对过去一年中每个月的呼吸道症状进行评分。记录常见呼吸道过敏原、葡萄霉菌和葡萄花粉的呼吸功能测试和皮肤点刺试验结果。

结果

纳入307名受试者。WRS的患病率为11%。与症状与工作无关的受试者相比，有WRS的受试者对禾本科植物致敏的频率更高（34%对18%，p = 0.05），出现眼部瘙痒（74%对37%，p < 0.001）和季节性症状（88%对69%，p = 0.03），主要在春季后期的举升和搭架作业期间（57%对17%，p < 0.001）。