非肥胖汉族成年人不同糖代谢状态下血清铁蛋白与胰岛素抵抗的关系。
The Relationship between Serum Ferritin and Insulin Resistance in Different Glucose Metabolism in Nonobese Han Adults.
机构信息
Department of Endocrinology, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Qinhuangdao, Hebei 066000, China.
出版信息
Int J Endocrinol. 2015;2015:642194. doi: 10.1155/2015/642194. Epub 2015 Aug 19.
Abstract
The exact mechanism through which elevated serum ferritin promotes the development of type 2 diabetes is unknown. This study showed that ferritin concentration in impaired glucose regulation and newly diagnosed diabetes mellitus subjects of nonobesity already significantly increased when compared with normal glucose tolerant subjects of nonobesity. Elevated serum ferritin levels are associated with insulin resistance and may be not associated with the decline of insulin beta cells in different status of glucose tolerance in nonobese Han adults.
摘要
目前尚不清楚血清铁蛋白升高促进 2 型糖尿病发展的确切机制。本研究表明，与非肥胖糖耐量正常者相比，葡萄糖调节受损和新诊断为糖尿病的非肥胖者的铁蛋白浓度已经明显升高。血清铁蛋白水平升高与胰岛素抵抗有关，但与非肥胖汉族成年人不同糖耐量状态下胰岛素β细胞的下降可能无关。
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