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采用应答者驱动抽样法在吉隆坡大都市区注射吸毒者中开展的艾滋病毒流行率研究

HIV Prevalence Among People Who Inject Drugs in Greater Kuala Lumpur Recruited Using Respondent-Driven Sampling.

作者信息

Bazazi Alexander R, Crawford Forrest, Zelenev Alexei, Heimer Robert, Kamarulzaman Adeeba, Altice Frederick L

机构信息

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.

Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

AIDS Behav. 2015 Dec;19(12):2347-57. doi: 10.1007/s10461-015-1191-y.

Abstract

The HIV epidemic in Malaysia is concentrated among people who inject drugs (PWID). Accurate estimates of HIV prevalence are critical for developing appropriate treatment and prevention interventions for PWID in Malaysia. In 2010, 461 PWID were recruited using respondent-driven sampling in Greater Kuala Lumpur, Malaysia. Participants completed rapid HIV testing and behavioral assessments. Estimates of HIV prevalence were computed for each of the three recruitment sites and the overall sample. HIV prevalence was 15.8 % (95 % CI 12.5-19.2 %) overall but varied widely by location: 37.0 % (28.6-45.4 %) in Kampung Baru, 10.3 % (5.0-15.6 %) in Kajang, and 6.3 % (3.0-9.5 %) in Shah Alam. Recruitment extended to locations far from initial interview sites but was concentrated around discrete geographic regions. We document the high prevalence of HIV among PWID in Greater Kuala Lumpur. Sustained support for community surveillance and HIV prevention interventions is needed to stem the HIV epidemic among PWID in Malaysia.

摘要

马来西亚的艾滋病毒疫情集中在注射毒品者中。准确估计艾滋病毒流行率对于为马来西亚的注射毒品者制定适当的治疗和预防干预措施至关重要。2010年,在马来西亚吉隆坡大都市区采用应答者驱动抽样法招募了461名注射毒品者。参与者完成了艾滋病毒快速检测和行为评估。计算了三个招募地点以及整个样本的艾滋病毒流行率估计值。总体艾滋病毒流行率为15.8%(95%可信区间12.5 - 19.2%),但因地点不同差异很大:甘榜峇鲁为37.0%(28.6 - 45.4%),加影为10.3%(5.0 - 15.6%),莎阿南为6.3%(3.0 - 9.5%)。招募范围扩大到远离初始访谈地点的地区,但集中在离散的地理区域周围。我们记录了吉隆坡大都市区注射毒品者中艾滋病毒的高流行率。需要持续支持社区监测和艾滋病毒预防干预措施,以遏制马来西亚注射毒品者中的艾滋病毒疫情。

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