Jang Eungyeong, Kim Bum-Joon, Lee Kyung-Tae, Inn Kyung-Soo, Lee Jang-Hoon
Department of Internal Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Department of Microbiology and Immunology, Liver Research Institute, Cancer Research Institute and SNUMRC, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Evid Based Complement Alternat Med. 2015;2015:728137. doi: 10.1155/2015/728137. Epub 2015 Aug 20.
Artemisia capillaris has been recognized as an herb with therapeutic efficacy in liver diseases and widely used as an alternative therapy in Asia. Numerous studies have reported the antisteatotic, antioxidant, anti-inflammatory, choleretic, antiviral, antifibrotic, and antitumor activities of A. capillaris. These reports support its therapeutic potential in various liver diseases such as chronic hepatitis B virus (HBV) infection, cirrhosis, and hepatocellular carcinoma. In addition, several properties of its various constituents, which provide clues to the underlying mechanisms of its therapeutic effects, have been studied. This review describes the scientific evidence supporting the therapeutic potential of A. capillaris and its constituents in various liver diseases.
茵陈蒿已被公认为是一种对肝脏疾病具有治疗功效的草药,并在亚洲被广泛用作替代疗法。大量研究报道了茵陈蒿的抗脂肪变性、抗氧化、抗炎、利胆、抗病毒、抗纤维化和抗肿瘤活性。这些报道支持了其在各种肝脏疾病如慢性乙型肝炎病毒(HBV)感染、肝硬化和肝细胞癌中的治疗潜力。此外,还对其各种成分的若干特性进行了研究,这些特性为其治疗作用的潜在机制提供了线索。本综述描述了支持茵陈蒿及其成分在各种肝脏疾病中治疗潜力的科学证据。