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一例肺部嗜酸性血管中心性纤维化的外科病例。

A surgical case of eosinophilic angiocentric fibrosis of the lung.

作者信息

Okamoto Keigo, Motoishi Makoto, Kaku Ryosuke, Sawai Satoru, Hanaoka Jun

机构信息

Department of General Thoracic Surgery, National Hospital Organization Kyoto Medical Center, 1-1 Mukaihatacho Fukakusa, Fushimi, Kyoto, 612-0862 Japan.

Department of General Thoracic Surgery, Shiga University of Medical Science, Tsukinowacho Seta Otsu, Shiga, 520-2121 Japan.

出版信息

Surg Case Rep. 2015;1(1):52. doi: 10.1186/s40792-015-0055-z. Epub 2015 Jun 17.

Abstract

Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory disease that develops from the respiratory organs and affects them. Almost all reports about EAF describe lesions affecting the upper respiratory tract. We present the first case of EAF of the lung treated by surgical excision. A 69-year-old female consulted our hospital following the detection of an abnormal chest shadow with chronic cough. Chest computed tomography showed a pulmonary growing mass in the right hilar area, which corresponded to an enhanced accumulation on positron emission tomography. We doubted a pulmonary malignant tumor and performed a right upper lobectomy. Pathological and other clinical presentations revealed EAF of the lung without coexisting systemic diseases. The patient had an uncomplicated postoperative course, and the presenting cough had improved. EAF can involve the lung and cause symptomatic airway obstruction. For a hilar region mass with imaging characteristics similar to those of lung cancer, a differential diagnosis must be considered.

摘要

嗜酸性粒细胞性血管中心性纤维化(EAF)是一种罕见的炎症性疾病,起源于呼吸器官并累及这些器官。几乎所有关于EAF的报告都描述了影响上呼吸道的病变。我们报告首例通过手术切除治疗的肺部EAF病例。一名69岁女性因慢性咳嗽发现胸部阴影异常后前来我院就诊。胸部计算机断层扫描显示右肺门区有一个肺部生长性肿块,正电子发射断层扫描显示有强化聚集。我们怀疑是肺部恶性肿瘤,遂进行了右上叶切除术。病理及其他临床表现显示为肺部EAF,无并存的全身性疾病。患者术后病程顺利,咳嗽症状有所改善。EAF可累及肺部并导致有症状的气道阻塞。对于具有类似于肺癌影像学特征的肺门区肿块,必须考虑进行鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed7/4883619/9112b829ff07/40792_2015_55_Fig1_HTML.jpg

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