Ishibashi Fumihiro, Moriya Yasumitsu, Tamura Hajime, Matsui Yukiko, Iizasa Toshihiko
Division of Thoracic Diseases, Chiba Cancer Center, 666-2, Nitona-cho, Chuo-ku, Chiba 260-8717 Japan.
Surg Case Rep. 2015;1(1):56. doi: 10.1186/s40792-015-0061-1. Epub 2015 Jul 8.
Primary intrapulmonary thymomas (PITs), which are intrapulmonary tumors without an associated mediastinal component, are very rare. The diagnosis of a PIT can be difficult. Here, we report two cases of resected PITs that were difficult to differentiate from other lung tumors. The patients, of a 62-year-old man and a 64-year-old woman, had no significant symptoms and were both referred to our hospital due to the presence of an abnormal shadow on chest computed tomography (CT). The patients underwent (18)F-fluorodeoxyglucose positron emission tomography-CT (FDG-PET/CT) and subsequently tumor excision. A PIT was confirmed histopathologically in the surgical specimens from both patients. In one case, the tumor consisted of a type A thymoma without abnormal FDG uptake. In the other case, the tumor consisted of a type B2 thymoma presenting with weak FDG uptake. This report thus documents two cases of PITs with different histopathologic and FDG-PET/CT findings. Thoracoscopic surgery is essential in the differential diagnosis between PITs and other lung tumors.
原发性肺内胸腺瘤（PITs）是指不伴有纵隔成分的肺内肿瘤，极为罕见。PIT的诊断可能具有挑战性。在此，我们报告两例经手术切除的PIT病例，这两例病例在与其他肺部肿瘤的鉴别诊断上存在困难。患者分别为一名62岁男性和一名64岁女性，均无明显症状，因胸部计算机断层扫描（CT）发现异常阴影而转诊至我院。患者接受了（18）F - 氟脱氧葡萄糖正电子发射断层扫描 - CT（FDG - PET/CT）检查，随后进行了肿瘤切除。手术标本经组织病理学检查确诊为PIT。其中一例肿瘤为A型胸腺瘤，FDG摄取无异常。另一例肿瘤为B2型胸腺瘤，FDG摄取较弱。本报告记录了两例具有不同组织病理学和FDG - PET/CT表现的PIT病例。胸腔镜手术对于PIT与其他肺部肿瘤的鉴别诊断至关重要。
