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新的接触过敏原:2008 年至 2015 年。

New Contact Allergens: 2008 to 2015.

机构信息

From Acdegroot Publishing, Wapserveen, The Netherlands.

出版信息

Dermatitis. 2015 Sep-Oct;26(5):199-215. doi: 10.1097/DER.0000000000000144.

Abstract

Every year, new contact allergens, chemicals reported to have caused contact allergy/ACD for the first time, are described in literature. In the journals Contact Dermatitis and Dermatitis, 172 such compounds were identified in the period 2008-2015, 119 of which induced ACD. These are presented with the following data: name, synonyms, Chemical Abstracts Service (CAS) number, patch test data, function or class, causative product, number of patients, occupation (in case of occupational ACD), additional clinical data (if applicable), and references. Approximately one third of the new allergens were ingredients of cosmetics, followed by drugs causing occupational ACD (18%), chemicals in rubber, plastics, and paints (9%), drugs causing a drug eruption (9%), as well as chemicals used in laboratories inducing occupational ACD (8%). In 40%, the dermatitis was occupationally acquired. Fifty-three other chemicals causing contact allergy as indicated by positive patch test reactions only are shown without specifics.

摘要

每年,新的接触过敏原,即首次被报道导致接触过敏/ACD 的化学物质,都会在文献中有所描述。在《接触性皮炎》和《皮炎》杂志上,2008 年至 2015 年间共确定了 172 种此类化合物,其中 119 种可引起 ACD。这些化合物的相关信息如下:名称、同义词、化学文摘服务(CAS)编号、斑贴试验数据、功能或类别、致病产品、患者人数、职业(若为职业性 ACD)、附加临床数据(如适用)和参考文献。约三分之一的新过敏原是化妆品的成分,其次是引起职业性 ACD 的药物(18%)、橡胶、塑料和油漆中的化学物质(9%)、引起药物性皮炎的药物(9%),以及在实验室中引起职业性 ACD 的化学物质(8%)。在 40%的情况下,皮炎是职业性获得的。另有 53 种其他化学物质仅因阳性斑贴试验反应而被认为可引起接触过敏,并未列出具体信息。

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