Li Yansheng, Wang Wenqian, Zhao Dan, Chen Peng, Du Hongwu, Wen Yongqiang, Zhang Xueji
J Nanosci Nanotechnol. 2015 Jun;15(6):4648-52. doi: 10.1166/jnn.2015.9810.
In this manuscript, we demonstrate a novel, facile and environmentally friendly method to directly obtain CdTe/ZnSe core/shell QDs in the aqueous phase based on the method of epitaxial growth of ZnSe shells on CdTe cores. The ZnSe shell and the capping reagent glutathione of the CdTe/ZnSe core/shell QDs greatly increased the biocompatibility and stability of the original CdTe cores. The optical property of the as-prepared CZ QDs could be controlled by precisely adjusting the size of CdTe cores, which showed broad emission spectra from 530 to 688 nm. The crystalline structure of the CZ QDs was extensively characterized by XRD, TEM and HRTEM, etc. Furthermore, since there were several functional groups on glutathione molecules, the QDs could be potentially used for connecting other functional small molecules, biomolecules or nanoparticles. Such QDs have bright future perspectives in the development biological and nanomedical fields.
在本手稿中，我们展示了一种新颖、简便且环境友好的方法，基于在CdTe核上外延生长ZnSe壳的方法，直接在水相中获得CdTe/ZnSe核壳量子点。CdTe/ZnSe核壳量子点的ZnSe壳和封端剂谷胱甘肽极大地提高了原始CdTe核的生物相容性和稳定性。通过精确调节CdTe核的尺寸，可以控制所制备的CZ量子点的光学性质，其发射光谱范围为530至688nm，呈现出较宽的发射光谱。通过XRD、TEM和HRTEM等手段对CZ量子点的晶体结构进行了广泛表征。此外，由于谷胱甘肽分子上存在多个官能团，这些量子点有可能用于连接其他功能性小分子、生物分子或纳米颗粒。此类量子点在生物和纳米医学领域的发展中具有光明的前景。
