Riboh Jonathan C, Cole Brian J, Farr Jack
Division of Sports Medicine, Rush University Medical Center, Chicago, IL, USA.
Cartilage Restoration Center of Indiana, Greenwood, IN, USA.
Curr Rev Musculoskelet Med. 2015 Dec;8(4):429-35. doi: 10.1007/s12178-015-9300-0.
The treatment of focal cartilage defects in the knee remains a challenging clinical problem. One relatively new unique treatment option is particulated articular cartilage, which includes autograft and off-the-shelf allogeneic juvenile grafts. The use of particulated cartilage has the advantage of being a single-stage procedure. In the case of autograft, it is cost efficient, while in the juvenile allograft form, it may have increased proliferative and restorative potentials. Laboratory and clinical data are limited for particulated cartilage grafts; however, there are promising histologic and clinical outcomes. This review provides a summary of the indications, surgical technique, and most up-to-date research on particulated cartilage for the repair of symptomatic chondral defects in the knee.
膝关节局灶性软骨缺损的治疗仍然是一个具有挑战性的临床问题。一种相对较新的独特治疗选择是颗粒状关节软骨,其中包括自体移植和现成的同种异体幼年移植物。使用颗粒状软骨的优点是为单阶段手术。对于自体移植,具有成本效益,而对于幼年同种异体移植形式,其可能具有更高的增殖和修复潜力。颗粒状软骨移植物的实验室和临床数据有限;然而,有令人鼓舞的组织学和临床结果。本综述总结了颗粒状软骨用于修复膝关节有症状软骨缺损的适应证、手术技术及最新研究。