Dirou S, Voiriot G
Service de pneumologie, l'institut du thorax, hôpital G.-et-R.-Laënnec, CHU de Nantes, boulevard J.-Monod, 44093 Nantes cedex 1, France.
Service de réanimation médicale et infectieuse, hôpital Bichat-Claude-Bernard, Assistance publique-hôpitaux de Paris, 75018 Paris, France.
Rev Mal Respir. 2015 Oct;32(8):841-4. doi: 10.1016/j.rmr.2015.06.001. Epub 2015 Sep 12.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in ambulatory medicine for their analgesic and antipyretic properties and are often used as self-medication. Their use in community-acquired pneumonia is associated with an increased risk of loco-regional complications, especially pleural empyema. Appropriate therapeutic care and hospital admissions are often delayed because of initial improvement of symptoms with NSAIDs. Despite worrying observational data, a causal link remains to be established. Currently, there is no recommendation cautioning against the use of NSAIDs in the management of community-acquired pneumonia.