Yasmin Seema, Adams Laura, Briggs Graham, Weiss Joli, Bisgard Kris, Anderson Shoana, Tsang Clarisse, Henke Evan, Vasiq Muhammad, Komatsu Ken
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA Arizona Department of Health Services, Phoenix, AZ, USA
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA Arizona Department of Health Services, Phoenix, AZ, USA.
J Correct Health Care. 2015 Oct;21(4):327-34. doi: 10.1177/1078345815604752.
The authors investigated the second botulism outbreak to occur in a maximum security prison in Arizona within a 4-month period. Botulism was confirmed in eight men aged 20 to 35 years who reported sharing a single batch of pruno made with potatoes. Initial symptoms included blurred vision, slurred speech, muscle weakness, ptosis, and dysphagia. All patients received heptavalent botulinum antitoxin, seven required mechanical ventilation, and all survived. The median incubation period was 29 hours. Sera from all patients and leftover pruno tested positive for botulinum toxin type A. Botulism should be considered among prisoners with cranial nerve palsies and descending, symmetric flaccid paralysis. Prison-brewed alcohol, particularly when made with potatoes, can be a vehicle for botulism and is associated with outbreaks of botulism in prisons.
作者调查了4个月内在亚利桑那州一所戒备森严的监狱发生的第二起肉毒中毒疫情。8名年龄在20至35岁的男性被确诊为肉毒中毒,他们报告称分享了一批用土豆制作的普诺酒。初始症状包括视力模糊、言语不清、肌肉无力、上睑下垂和吞咽困难。所有患者均接受了七价肉毒抗毒素治疗,7人需要机械通气,所有患者均存活。中位潜伏期为29小时。所有患者的血清和剩余的普诺酒检测出A型肉毒毒素呈阳性。对于出现颅神经麻痹和下行性、对称性弛缓性麻痹的囚犯,应考虑肉毒中毒的可能。监狱自酿的酒,尤其是用土豆制作的,可能是肉毒中毒的传播媒介,并与监狱内的肉毒中毒疫情有关。