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肝转移为主的转移性结直肠癌的肝内治疗

Intrahepatic therapy for liver-dominant metastatic colorectal cancer.

作者信息

De Groote Kerlijne, Prenen Hans

机构信息

Kerlijne De Groote, Hans Prenen, Department of Gastroenterology, University Hospitals Leuven, B-3000 Leuven, Belgium.

出版信息

World J Gastrointest Oncol. 2015 Sep 15;7(9):148-52. doi: 10.4251/wjgo.v7.i9.148.

Abstract

In patients with metastatic colorectal cancer, the liver is the most common site of metastatic disease. In patients with liver-dominant disease, consideration needs to be given to locoregional treatments such as hepatic arterial infusion chemotherapy, transarterial chemoembolisation and selective internal radiation therapy because hepatic metastases are a major cause of liver failure especially in chemorefractory disease. In this review we provide insights on the published literature for locoregional treatment of liver metastases in metastatic colorectal cancer.

摘要

在转移性结直肠癌患者中,肝脏是最常见的转移部位。对于以肝脏转移为主的患者,需要考虑局部区域治疗,如肝动脉灌注化疗、经动脉化疗栓塞和选择性内放射治疗,因为肝转移是肝衰竭的主要原因,尤其是在化疗难治性疾病中。在本综述中,我们对已发表的关于转移性结直肠癌肝转移局部区域治疗的文献进行了深入分析。

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本文引用的文献

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Oncological management of unresectable liver metastases.
Dig Dis. 2012;30 Suppl 2:137-42. doi: 10.1159/000342047. Epub 2012 Nov 23.

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