Rigotti Clara F, Jolliffe Colette T, Leece Elizabeth A
J Am Vet Med Assoc. 2015 Oct 1;247(7):765-70. doi: 10.2460/javma.247.7.765.
To investigate whether prewarming affects body temperature of small dogs (weighing < 10 kg [22 lb]) undergoing inhalation anesthesia.
Prospective, randomized, blinded clinical trial. Animals: 20 dogs weighing < 10 kg with American Society of Anesthesiologists physical status I or II.
Baseline rectal temperature was recorded. Before IM administration of buprenorphine hydrochloride and acepromazine maleate, dogs were randomly assigned to be placed in a pediatric incubator at 33°C (91.4°F) for approximately 30 to 60 minutes (prewarming group) or to receive no prewarming (control group); subsequently, dogs underwent inhalation anesthesia with isoflurane in oxygen. Rectal, esophageal, and ambient temperatures were measured every 5 minutes from induction of anesthesia (IOA) for > 1 hour by an observer who was unaware of treatment. If a dog became hypothermic (esophageal temperature < 36°C [96.8°F]), it was withdrawn from the study. Variables of interest relating to dogs, anesthesia, temperatures, hypothermia, and study withdrawal were compared between groups.
1 dog was excluded from the prewarming group after becoming excessively excited in the incubator. Between groups, age, weight, body condition score, degree of preanesthesia sedation, interval from sedation to IOA, duration of anesthesia, baseline rectal temperature, rectal temperatures immediately prior to IOA, esophageal temperature following IOA, ambient temperature during the first 70 minutes of anesthesia, esophageal or rectal temperature during the first 90 minutes of anesthesia, and incidence of hypothermia and study withdrawal (5 dogs/group) did not differ significantly.
Prewarming in an incubator prior to IOA failed to improve or maintain body temperature of dogs weighing < 10 kg during inhalation anesthesia.
探讨预加温是否会影响接受吸入麻醉的小型犬（体重<10千克[22磅]）的体温。
前瞻性、随机、盲法临床试验。动物：20只体重<10千克、美国麻醉医师协会身体状况为I或II级的犬。
记录基础直肠温度。在肌肉注射盐酸丁丙诺啡和马来酸乙酰丙嗪之前，将犬随机分为两组，一组置于33°C（91.4°F）的儿科保温箱中约30至60分钟（预加温组），另一组不进行预加温（对照组）；随后，犬接受异氟烷和氧气的吸入麻醉。由一名不了解治疗分组情况的观察者在麻醉诱导后每5分钟测量直肠、食管和环境温度，持续1小时以上。如果犬出现体温过低（食管温度<36°C[96.8°F]），则将其排除出研究。比较两组之间与犬、麻醉、温度、体温过低和研究排除相关的感兴趣变量。
预加温组中有1只犬在保温箱中过度兴奋后被排除。两组之间，年龄、体重、身体状况评分、麻醉前镇静程度、从镇静到麻醉诱导的间隔时间、麻醉持续时间、基础直肠温度、麻醉诱导前即刻的直肠温度、麻醉诱导后的食管温度、麻醉前70分钟的环境温度、麻醉前90分钟的食管或直肠温度，以及体温过低和研究排除的发生率（每组5只犬）均无显著差异。
在麻醉诱导前于保温箱中进行预加温未能改善或维持体重<10千克的犬在吸入麻醉期间的体温。
