Hofmeister Erik H, Brainard Benjamin M, Braun Christina, Figueiredo Juliana P
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
J Am Vet Med Assoc. 2011 Dec 15;239(12):1561-5. doi: 10.2460/javma.239.12.1561.
To determine whether a heat and moisture exchange device (HME) prevents a decrease in body temperature in isoflurane-anesthetized dogs undergoing orthopedic procedures.
Blinded randomized controlled clinical trial.
60 privately owned dogs weighing at least 15 kg (33 lb).
Dogs were randomly assigned to 1 of 3 treatment groups (n = 20/group): HME placed immediately after anesthetic induction with isoflurane, after transfer to the operating room, or not at all. The device consisted of a hygroscopic filter placed between the endotracheal tube and the Y piece of the anesthesia circuit. Each dog was positioned on a circulating warm water blanket and had a forced-air warming blanket placed over its body. Body temperature was monitored after transfer to the operating room with a probe placed in the thoracic aspect of the esophagus.
Study groups did not differ significantly with respect to body weight, body condition score, reproductive status, breed, surgical procedure, preoperative sedative and opioid administration, anesthetic induction drug, local nerve block technique, or operating room assignment. There were no significant differences among groups in esophageal temperature variables, interval between anesthetic induction and surgery, surgery duration, anesthesia duration, or oxygen flow rate. However, the relationship between temperature delta and body weight was significant and relevant (R(2) = 0.23), as was the association between temperature nadir and body weight (R(2)= 0.10). As body weight increased, the temperature delta decreased and temperature nadir increased. No other significant relationships were identified.
Inclusion of an HME in healthy dogs undergoing anesthesia for an elective orthopedic surgery did not facilitate maintenance of body temperature throughout the procedure.
确定热湿交换装置(HME)能否防止接受骨科手术的异氟烷麻醉犬的体温下降。
双盲随机对照临床试验。
60只体重至少15千克(33磅)的家养犬。
犬被随机分配到3个治疗组之一(每组n = 20):异氟烷麻醉诱导后立即放置HME、转移至手术室后放置HME或根本不放置HME。该装置由置于气管内导管和麻醉回路Y形接头之间的吸湿过滤器组成。每只犬均置于循环温水毯上,并在其身体上放置一个强制空气加温毯。转移至手术室后,用置于食管胸段的探头监测体温。
研究组在体重、身体状况评分、生殖状态、品种、手术程序、术前镇静剂和阿片类药物给药、麻醉诱导药物、局部神经阻滞技术或手术室分配方面无显著差异。各组在食管温度变量、麻醉诱导与手术间隔、手术持续时间、麻醉持续时间或氧流量方面无显著差异。然而,体温变化幅度与体重之间的关系显著且相关(R² = 0.23),体温最低点与体重之间的关联也如此(R² = 0.10)。随着体重增加,体温变化幅度减小,体温最低点升高。未发现其他显著关系。
对于接受择期骨科手术麻醉的健康犬,使用HME并不能在整个手术过程中促进体温维持。