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梅毒治疗流程:追踪秘鲁利马男性及与男性发生性行为的跨性别女性梅毒筛查呈阳性后的治疗过程。

The syphilis care cascade: tracking the course of care after screening positive among men and transgender women who have sex with men in Lima, Peru.

作者信息

Tang Eric C, Segura Eddy R, Clark Jesse L, Sanchez Jorge, Lama Javier R

机构信息

Department of Medicine/Division of Infectious Diseases, UCLA Geffen School of Medicine, Los Angeles, California, USA.

Asociación Civil Impacta Salud y Educación, Lima, Peru Department of Global Health, University of Washington, Seattle, Washington, USA.

出版信息

BMJ Open. 2015 Sep 18;5(9):e008552. doi: 10.1136/bmjopen-2015-008552.

Abstract

OBJECTIVES

Syphilis is endemic among men who have sex with men (MSM) and transgender women in Latin America. The objective of this study was to assess if those who screen positive for syphilis are receiving appropriate care and treatment.

METHODS

We use data from the 2011 Peruvian National HIV Sentinel Surveillance to describe the syphilis care cascade among high-risk MSM and transgender women. Medical records from participants who had a positive syphilis screening test at two of the enrolment sites in Lima were reviewed to determine their subsequent course of care.

RESULTS

We identified a cohort of 314 syphilis seropositive participants (median age: 30, 33.7% self-identified as transgender). Only 284/314 (90.4%) participants saw a physician for evaluation within 28 days of their positive test. Of these, 72/284 (25.4%) were asked to return for confirmatory results before deciding whether or not to start treatment; however, 45/72 (62.5%) of these participants did not follow up within 28 days. Of the people prescribed three weekly doses of penicillin, 34/63 (54%) received all three doses on time.

CONCLUSIONS

Many MSM and transgender women with a positive syphilis screening test are lost at various steps along the syphilis care cascade and may have persistent infection. Interventions in this population are needed to increase testing, link seropositive patients into care and ensure that they receive appropriate and timely treatment.

摘要

目的

梅毒在拉丁美洲的男男性行为者(MSM)和变性女性中呈地方性流行。本研究的目的是评估梅毒筛查呈阳性的人是否得到了适当的护理和治疗。

方法

我们使用2011年秘鲁全国艾滋病毒哨点监测的数据来描述高危男男性行为者和变性女性中的梅毒护理流程。对在利马两个登记点梅毒筛查试验呈阳性的参与者的病历进行了审查,以确定他们随后的护理过程。

结果

我们确定了一组314名梅毒血清学阳性参与者(中位年龄:30岁,33.7%自我认定为变性者)。只有284/314(90.4%)的参与者在检测呈阳性后的28天内看医生进行评估。其中,72/284(25.4%)在决定是否开始治疗前被要求返回获取确认结果;然而,这些参与者中有45/72(62.5%)在28天内没有进行随访。在被开了三周青霉素剂量的人中,34/63(54%)按时接受了所有三剂。

结论

许多梅毒筛查呈阳性的男男性行为者和变性女性在梅毒护理流程的各个环节中流失,可能存在持续性感染。需要对这一人群进行干预,以增加检测,将血清学阳性患者纳入护理,并确保他们得到适当和及时的治疗。

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