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基于场所的 HIV 检测:秘鲁利马高危人群的有效筛查策略。

Venue-Based HIV-Testing: An Effective Screening Strategy for High-Risk Populations in Lima, Peru.

机构信息

David Geffen School of Medicine, University of California, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA.

Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA.

出版信息

AIDS Behav. 2019 Apr;23(4):813-819. doi: 10.1007/s10461-018-2342-8.

Abstract

Venue-based testing may improve screening efforts for HIV and syphilis, thereby reducing transmission. We offered onsite rapid dual HIV and syphilis testing at venues popular among MSM and/or transgender women in Lima, Peru. We used Poisson regression to calculate adjusted prevalence ratios (aPRs) for factors associated with each infection. Most (90.4%) of the 303 participants would test more frequently if testing was available at alternative venues. New cases of HIV (69) and syphilis infection (84) were identified. HIV was associated with recent sex work (aPR 1.11; 95% CI 1.02-1.22), sex with a partner of unknown serostatus (aPR 1.18; 95% CI 1.09-1.27), exclusively receptive anal sex role (aPR 1.16; 95% CI 1.03-1.30) or versatile sex role (aPR 1.17; 95% CI 1.06-1.30) compared to insertive. Syphilis was associated with reporting role versatility (aPR = 2.69; 95% CI 1.52-5.74). Sex work venues had higher syphilis prevalence 47% versus 28% in other venues, p value = 0.012. Venue-based testing may improve case finding.

摘要

基于场所的检测可能会改善艾滋病毒和梅毒的筛查工作,从而减少传播。我们在秘鲁利马男男性行为者和/或跨性别女性中流行的场所提供现场快速双重艾滋病毒和梅毒检测。我们使用泊松回归计算与每种感染相关的因素的调整患病率比 (aPR)。如果在其他场所提供检测,303 名参与者中的大多数(90.4%)将更频繁地进行检测。发现了 69 例新的艾滋病毒病例和 84 例梅毒感染病例。艾滋病毒与最近的性工作(aPR 1.11;95%CI 1.02-1.22)、与未知血清状况的伴侣发生性行为(aPR 1.18;95%CI 1.09-1.27)、仅接受肛交角色(aPR 1.16;95%CI 1.03-1.30)或万能性角色(aPR 1.17;95%CI 1.06-1.30)相关,而不是插入性。梅毒与报告角色多样性有关(aPR=2.69;95%CI 1.52-5.74)。性工作场所的梅毒患病率较高,为 47%,而其他场所为 28%,p 值=0.012。基于场所的检测可能会改善病例发现。

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