Intraosseous Schwannoma Involving Multiple Bones of the Foot: A Case Report.

We describe a rare case of intraosseous Schwannoma in the foot involving the tarsal navicular, cuboid, all 3 cuneiforms, and the second and third metatarsal bases in a 50-year-old female. Radiographs revealed a large, well-defined osteolytic lesion with endosteal scalloping and trabeculated contours at the margins. Intralesional excision, allograft bone implantation, and Kirschner wire fixation were performed. The histologic and immunohistochemical studies confirmed the diagnosis of Schwannoma. The distinctive radiographic features might have been the result of tumor spreading within the nutrient canals of the bones and direct compression of bone as the tumor enlarged. At the 18-month follow-up point, the patient had recovered well without recurrence. Intralesional excision produced a good functional outcome; however, extensive fusion surgery is recommended.