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[癫痫患者的单光子发射计算机断层扫描(SPECT)、脑电图(EEG)与计算机断层扫描(CT)的相关性。初步报告]

[Correlation of SPECT, EEG and CT in patients with epilepsy. A preliminary report].

作者信息

Qu Z

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1989 Dec;22(6):341-3, 382.

PMID:2638985
Abstract

Single photon emission computed tomography (SPECT) were performed in 14 patients with epilepsy. Among 6 patients with GTC, five had no focal abnormalities in EEG and CT scan, SPECT also showed no changes of regional cerebral perfusion. In another one patient EEG was normal, CT scan showed hypodensity in right frontal area, SPECT showed decreased regional cerebral perfusion in right frontotemporal area. AVM in frontal lobe was found at operation. In 3 patients with complex partial seizures and 5 patients with complex partial seizures and GTC, SPECT showed regional cerebral perfusion coincided with the area of focal epileptic form discharges in EEG. In one patient with complex partial seizures and GTC EEG showed right antero-temporal focal sharp wave discharges, discrete calcification in superior suprasella cisterna on CT, SPECT showed decreased regional perfusion in right temporal area, pathological examination revealed hematoma in right temporal lobe. SPECT is useful for localizing epileptogenic foci in epileptics.

摘要

对14例癫痫患者进行了单光子发射计算机断层扫描(SPECT)检查。在6例全面性强直阵挛发作(GTC)患者中,5例脑电图(EEG)和CT扫描无局灶性异常,SPECT也显示局部脑灌注无变化。另一例患者EEG正常,CT扫描显示右侧额叶低密度,SPECT显示右侧额颞叶局部脑灌注降低。手术中发现额叶动静脉畸形(AVM)。在3例复杂部分性发作患者以及5例复杂部分性发作合并GTC患者中,SPECT显示局部脑灌注与EEG中局灶性癫痫样放电区域相符。1例复杂部分性发作合并GTC患者EEG显示右侧前颞叶局灶性尖波放电,CT显示鞍上池上方离散性钙化,SPECT显示右侧颞叶局部灌注降低,病理检查发现右侧颞叶血肿。SPECT有助于癫痫患者致痫灶的定位。

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