Expansion size and presence of CCG/CTC/CGG sequence interruptions in the expanded CTG array are independently associated to hypermethylation at the DMPK locus in myotonic dystrophy type 1 (DM1).
作者信息
Santoro Massimo, Fontana Luana, Masciullo Marcella, Bianchi Maria Laura Ester, Rossi Salvatore, Leoncini Emanuele, Novelli Giuseppe, Botta Annalisa, Silvestri Gabriella
机构信息
Fondazione Don Carlo Gnocchi, Via Capecelatro 66, 20148 Milan, Italy.
Department of Biomedicine and Prevention, University of Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
出版信息
Biochim Biophys Acta. 2015 Dec;1852(12):2645-52. doi: 10.1016/j.bbadis.2015.09.007. Epub 2015 Sep 21.
PMID:26391753
Abstract
摘要
Zotero 插件