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具有高稳定性和可重复使用性的聚多巴胺连接酶/金属有机框架复合材料

Polydopamine tethered enzyme/metal-organic framework composites with high stability and reusability.

作者信息

Wu Xiaoling, Yang Cheng, Ge Jun, Liu Zheng

机构信息

Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.

出版信息

Nanoscale. 2015 Dec 7;7(45):18883-6. doi: 10.1039/c5nr05190h. Epub 2015 Sep 22.

Abstract

An enzyme/metal-organic framework (MOF) composite with both highly stable and easily reusable features was prepared via tethering enzyme/MOF nanocrystals with polydopamine (PDA). The micrometer-sized PDA tethered enzyme/MOF composite can be easily repeatedly used without obvious activity loss, promising for efficient enzymatic catalysis at low cost with long-term operational stability under harsh conditions.

摘要

通过用聚多巴胺(PDA)连接酶/MOF纳米晶体,制备了一种兼具高稳定性和易于重复使用特性的酶/金属有机框架(MOF)复合材料。微米级的PDA连接酶/MOF复合材料可以很容易地反复使用而没有明显的活性损失,有望在苛刻条件下以低成本实现高效酶催化,并具有长期操作稳定性。

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