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[评估FIBS制剂治疗对葡萄膜炎患者临床状态及免疫系统各项参数的影响]

[Evaluation of the effect of treatment with FIBS preparation on the clinical state and various parameters of the immune system in patients with uveitis].

作者信息

Puchalska-Niedbał L

出版信息

Ann Acad Med Stetin. 1989;35:179-88.

PMID:2639596
Abstract

The study material comprised 60 patients treated at the Clinic of Ophthalmology PMA in Szczecin, in the years from 1981 to 1984 due to uveitis. In the patients routine laboratory examinations were performed and extended by additional ones in the direction of diseases being of rheumatoidal type, tuberculosis, toxoplasmosis, diabetes and focal infections. All the patients had rosette tests of E, EA, EAC prior to treatment and after 30 days of therapy. The patients were divided at random into 2 groups with 30 persons each. Apart from typical treatment for uveitis the group I was given the FIBS preparation. The clinical picture failed to reveal any significant differences between the groups of patients. It was observed that the count of lymphocytes T and B in the peripheral blood was disturbed. After the applied treatment changes were recorded in the count of lymphocytes T and B, the shiftings in the group of patients, having been treated with FIBS, were marked more distinctly, particularly in the count of lymphocytes T.

摘要

研究材料包括1981年至1984年期间因葡萄膜炎在什切青的波美拉尼亚医科大学眼科诊所接受治疗的60名患者。对这些患者进行了常规实验室检查,并针对类风湿性疾病、结核病、弓形虫病、糖尿病和局灶性感染方向进行了额外检查。所有患者在治疗前和治疗30天后均进行了E、EA、EAC玫瑰花结试验。患者被随机分为两组,每组30人。除了葡萄膜炎的典型治疗外,第一组还给予了FIBS制剂。临床症状未显示两组患者之间有任何显著差异。观察到外周血中T淋巴细胞和B淋巴细胞计数紊乱。经过应用治疗后,记录了T淋巴细胞和B淋巴细胞计数的变化,接受FIBS治疗的患者组中的变化更为明显,尤其是T淋巴细胞计数。

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