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[肾病中葡萄膜炎的诊断、免疫发病机制、临床表现及治疗]

[Diagnosis, immunopathogenesis, clinical picture and treatment of uveitis in nephropathies].

作者信息

Teplinskaia L E, Kaliberdina A F

出版信息

Vestn Oftalmol. 2000 Sep-Oct;116(5):39-42.

PMID:11221380
Abstract

Complex clinical and immunological studies in 39 patients with uveitis and a history of nephropathies disclosed a relationship between renal diseases and vascular tract of the eyes. Specific features in the clinical symptomatology and immunological disorders were detected. Anterior and generalized forms, bilateral involvement, Tyndall's symptom, combined vitreolenticular changes, often with the exudative hemorrhagic component, predominated in the clinical picture of uveitis in patients with nephropathies. Uveitis ran a protracted course resistant to therapy, with frequent relapses. The disease occurred mainly in women. Predominant disorders in immunopathogenesis were disorders in the complex formation system. Uveitis in patients with nephropathies should be treated with due consideration for the etiology of nephropathy, clinical course of uveitis, and immunological disorders. Diseases of the vascular tract associated with nephropathy are rare in the etiological structure of uveitis and retinovasculitis (3.24%).

摘要

对39例患有葡萄膜炎且有肾病病史的患者进行的复杂临床和免疫学研究揭示了肾脏疾病与眼部血管系统之间的关系。检测到临床症状和免疫紊乱的特定特征。肾病患者葡萄膜炎的临床症状中,前部和全身性形式、双侧受累、廷德尔征、玻璃体晶状体联合改变(常伴有渗出性出血成分)占主导。葡萄膜炎病程迁延,对治疗有抵抗性,且频繁复发。该疾病主要发生在女性。免疫发病机制中的主要紊乱是复合物形成系统的紊乱。肾病患者的葡萄膜炎治疗应充分考虑肾病的病因、葡萄膜炎的临床病程和免疫紊乱。与肾病相关的血管系统疾病在葡萄膜炎和视网膜血管炎的病因结构中很少见(3.24%)。

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