Horowitz S H, Ginsberg-Fellner F
Muscle Nerve. 1978 Sep-Oct;1(5):388-91. doi: 10.1002/mus.880010507.
The stability of sensory conduction and evoked potentials during ischemia has been used in the evaluation of diabetic neuropathy and diabetic control (Hgb A1C). Six newly diagnosed juvenile diabetics were studied at diagnosis and 3 to 12 months later. In three patients in good control, ischemic "resistance" became normal. In three patients in poor control, resistance remained increased; two of these three experienced a 10%-20% slowing in conduction velocity. Similar relationships between control and ischemic resistance are found in long-term diabetics. These data suggest that abnormal ischemic resistance may herald the onset of an electrical and clinical neuropathic state.
缺血期间感觉传导和诱发电位的稳定性已被用于评估糖尿病性神经病变和糖尿病控制情况(糖化血红蛋白)。对6名新诊断的青少年糖尿病患者在诊断时及3至12个月后进行了研究。在3名控制良好的患者中,缺血“抵抗”恢复正常。在3名控制不佳的患者中,抵抗仍然增加;这3名患者中有2名传导速度减慢了10%-20%。在长期糖尿病患者中也发现了控制与缺血抵抗之间的类似关系。这些数据表明,异常的缺血抵抗可能预示着电和临床神经病变状态的开始。