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糖尿病患儿及青少年的神经病变

Neuropathy in children and adolescents with diabetes mellitus.

作者信息

Gallai V, Firenze C, Mazzotta G, Del Gatto F

机构信息

Department of Neurology, University of Perugia, Italy.

出版信息

Acta Neurol Scand. 1988 Aug;78(2):136-40. doi: 10.1111/j.1600-0404.1988.tb03634.x.

Abstract

Nerve conduction velocities were studied in the median, posterior tibial, radial and sural nerves of 50 juvenile diabetics, average age 13 +/- 1.3 years and mean duration of diabetes 2.3 +/- 1.4 years. Motor conduction velocity (MCV) in the median nerve was reduced in 10% of the subjects, and in the posterior tibial in 32%. Sensory conduction velocity (SCV) in the radial nerve was reduced in 30% of the subjects, and in the sural in 44%. No relationship was found between the reduction in conduction velocity and the duration of diabetes; nevertheless, a correlation was observed between this reduction and the degree of glycaemic control represented by the glycosylated haemoglobin concentration. The authors emphasize the importance of good glycaemic control for the prevention of diabetic neuropathy.

摘要

对50名青少年糖尿病患者的正中神经、胫后神经、桡神经和腓肠神经的神经传导速度进行了研究,这些患者的平均年龄为13±1.3岁,糖尿病平均病程为2.3±1.4年。10%的受试者正中神经运动传导速度(MCV)降低,32%的受试者胫后神经运动传导速度降低。30%的受试者桡神经感觉传导速度(SCV)降低,44%的受试者腓肠神经感觉传导速度降低。未发现传导速度降低与糖尿病病程之间存在关联;然而,观察到这种降低与糖化血红蛋白浓度所代表的血糖控制程度之间存在相关性。作者强调良好的血糖控制对预防糖尿病神经病变的重要性。

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