Hasegawa R, Nakaji Y, Kurokawa Y, Tobe M
Sci Rep Res Inst Tohoku Univ Med. 1989 Dec;36(1-4):10-6.
Acute toxicity tests on 113 environmental chemicals were conducted by the order of the Japanese government agencies. the LD50s or LC50s for 23 household chemicals, 11 medical drugs, 10 drug additives, 20 food additives, 13 industrial chemicals, 14 environmental pollutants, 12 agricultural chemicals and 5 organic solvents are presented together with the major toxic signs and symptoms and macroscopic changes in tissues. These toxicity data will be useful as an information source for regulatory purposes and also for prediction of the potential for acute toxicity of a wide variety of new chemicals.
应日本政府机构的要求,对113种环境化学品进行了急性毒性试验。列出了23种家用化学品、11种药品、10种药物添加剂、20种食品添加剂、13种工业化学品、14种环境污染物、12种农药和5种有机溶剂的半数致死剂量(LD50)或半数致死浓度(LC50),以及主要的毒性体征和症状和组织的宏观变化。这些毒性数据将作为监管目的的信息来源,也有助于预测各种新化学品的急性毒性潜力。