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择期剖宫产术中的失血:与麻醉方式有关吗?一项随机前瞻性研究。

Blood loss in elective cesarean section: is there a difference related to the type of anesthesia? A randomized prospective study.

作者信息

Aksoy Hüseyin, Aksoy Ülkü, Yücel Burak, Özyurt Sezin Saygı, Açmaz Gökhan, Babayiğit Mustafa Alparslan, Gökahmetoğlu Günhan, Aydın Turgut

机构信息

Department of Obstetrics and Gynecology, Kayseri Military Hospital, Kayseri, Turkey.

Department of Obstetrics and Gynecology, Kayseri Memorial Hospital, Kayseri, Turkey.

出版信息

J Turk Ger Gynecol Assoc. 2015 Jul 14;16(3):158-63. doi: 10.5152/jtgga.2015.15034. eCollection 2015.

Abstract

OBJECTIVE

We aimed to compare the effect of general and spinal anesthesia on maternal blood loss in elective cesarean section (CS).

MATERIAL AND METHODS

This was a prospective randomized study and included 418 healthy pregnant women with a term uncomplicated singleton pregnancy between 37 and 41 weeks of gestation. The study participants were randomly divided into two groups: the general anesthesia group and spinal anesthesia group. CSs were all performed using the same surgical technique, and within the groups, the same anesthetic procedures were used (either general or spinal). The primary outcome for this study was operative blood loss. Hemoglobin and hematocrit concentrations were compared between the two groups.

RESULTS

The preoperative hemoglobin and hematocrit levels were similar in the both groups (p=0.08 and p=0.239, respectively). Significantly lower operative blood loss was achieved using spinal anesthesia versus general anesthesia during elective CS. The differences between preoperative and postoperative blood values for both the study groups were statistically significant (p<0.001).

CONCLUSION

This study demonstrates that spinal anesthesia is associated with a lower risk of operative blood loss than general anesthesia in low risk patients undergoing elective CS.

摘要

目的

我们旨在比较全身麻醉和脊髓麻醉对择期剖宫产术中产妇失血的影响。

材料与方法

这是一项前瞻性随机研究,纳入了418例孕周在37至41周、单胎妊娠且无并发症的健康孕妇。研究参与者被随机分为两组:全身麻醉组和脊髓麻醉组。所有剖宫产均采用相同的手术技术,且在组内采用相同的麻醉程序(全身麻醉或脊髓麻醉)。本研究的主要结局是术中失血量。比较两组的血红蛋白和血细胞比容浓度。

结果

两组术前血红蛋白和血细胞比容水平相似(分别为p = 0.08和p = 0.239)。在择期剖宫产术中,与全身麻醉相比,脊髓麻醉的术中失血量显著更低。两个研究组术前和术后血液值的差异具有统计学意义(p < 0.001)。

结论

本研究表明,在接受择期剖宫产的低风险患者中,脊髓麻醉与全身麻醉相比,术中失血风险更低。

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