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多叶准直器的圆形叶端对半影宽度和辐射野偏移的影响:一项分析与数值研究。

Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study.

作者信息

Zhou Dong, Zhang Hui, Ye Peiqing

机构信息

Department of Mechanical Engineering, Tsinghua University, Beijing, China.

出版信息

Radiol Oncol. 2015 Aug 21;49(3):299-306. doi: 10.1515/raon-2015-0023. eCollection 2015 Sep.

Abstract

BACKGROUND

Penumbra characteristics play a significant role in dose delivery accuracy for radiation therapy. For treatment planning, penumbra width and radiation field offset strongly influence target dose conformity and organ at risk sparing.

METHODS

In this study, we present an analytical and numerical approach for evaluation of the rounded leaf end effect on penumbra characteristics. Based on the rule of half-value layer, algorithms for leaf position calculation and radiation field offset correction were developed, which were advantageous particularly in dealing with large radius leaf end. Computer simulation was performed based on the Monte Carlo codes of EGSnrc/BEAMnrc, with groups of leaf end radii and source sizes. Data processing technique of curve fitting was employed for deriving penumbra width and radiation field offset.

RESULTS

Results showed that penumbra width increased with source size. Penumbra width curves for large radius leaf end were U-shaped. This observation was probably related to the fact that radiation beams penetrated through the proximal and distal leaf sides. In contrast, source size had negligible impact on radiation field offset. Radiation field offsets were found to be constant both for analytical method and numerical simulation. However, the overall resulting values of radiation field offset obtained by analytical method were slightly smaller compared with Monte Carlo simulation.

CONCLUSIONS

The method we proposed could provide insight into the investigation of rounded leaf end effects on penumbra characteristics. Penumbra width and radiation field offset calibration should be carefully performed to commission multileaf collimator for intensity modulated radiotherapy.

摘要

背景

半影特征在放射治疗的剂量传递准确性中起着重要作用。对于治疗计划,半影宽度和辐射野偏移对靶区剂量适形度和危及器官的保护有很大影响。

方法

在本研究中,我们提出了一种分析和数值方法来评估圆形叶片末端对半影特征的影响。基于半值层规则,开发了叶片位置计算和辐射野偏移校正算法,这在处理大半径叶片末端时特别有利。基于EGSnrc/BEAMnrc的蒙特卡罗代码进行了计算机模拟,设置了多组叶片末端半径和源尺寸。采用曲线拟合的数据处理技术来推导半影宽度和辐射野偏移。

结果

结果表明,半影宽度随源尺寸增加。大半径叶片末端的半影宽度曲线呈U形。这一观察结果可能与辐射束穿透叶片近端和远端有关。相比之下,源尺寸对辐射野偏移的影响可忽略不计。发现分析方法和数值模拟的辐射野偏移均为常数。然而,分析方法得到的辐射野偏移总体结果值与蒙特卡罗模拟相比略小。

结论

我们提出的方法可为研究圆形叶片末端对半影特征的影响提供见解。在调强放射治疗中调试多叶准直器时,应仔细进行半影宽度和辐射野偏移校准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d29b/4577228/ee35fa30c725/rado-49-03-299f1.jpg

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