Zhang Xiang, Ye Peiqing, Zhang Hui
Department of Mechanical Engineering, Tsinghua University, Beijing, 100084, China.
Beijing Key Lab of Precision/Ultra-Precision Manufacturing Equipments and Control, Tsinghua University, Beijing, 100084, China.
J Appl Clin Med Phys. 2017 Jan;18(1):96-106. doi: 10.1002/acm2.12026. Epub 2016 Dec 29.
Multileaf collimator (MLC) tracking represents a promising technique for motion management in radiotherapy. However, the conflict between limited leaf speed/acceleration and the demand for tracking fast target motion is now a prominent issue. Conventional MLCs typically have a maximum leaf speed of 3-4 cm/s and a maximum leaf acceleration of 50-70 cm/s, which are inadequate to track fast target motion. To cope with this problem, we have recently developed a high-speed multileaf collimator (HS-MLC) prototype, which employs linear motors instead of rotary motors to drive leaves. Consequently, it inherits various benefits of linear motors, including direct drive and high dynamics. The primary aim of this paper was to introduce the development and performance evaluation of the HS-MLC. The evaluation includes Monte Carlo simulations of the basic dosimetric properties, camera-based measurements of the mechanical properties and tracking experiments for 25 sets of patient-measured motion data. The Monte Carlo simulation results show that the maximum leakage at 6MV is 1.29% and the average is 0.61%. The end-to-end leakage is 3.96% for 5 cm offset and is 1.75% for 10 cm offset. The penumbra for a standard 10 × 10 cm field ranges from 4.8 mm to 5.4 mm across the full range of leaf motion. The mechanical property measurements demonstrate that the maximum leaf speed is 40 cm/s, the maximum leaf acceleration is 1000 cm/s, and the geometric accuracy can be kept within 0.5 mm. Regarding the tracking experiments for a wide range of motion patterns (fast breathing, irregular breathing, etc.), a root-mean-square error (RMSE) of less than 0.19 mm was achieved. In conclusion, the HS-MLC is able to well track fast target motion that is beyond the capability of conventional MLCs due to its superior mechanical properties. The new MLC design provides a feasible solution to make high-accuracy and high-efficiency motion management possible.
多叶准直器(MLC)跟踪是放射治疗中一种很有前景的运动管理技术。然而,有限的叶片速度/加速度与快速跟踪目标运动需求之间的矛盾如今已成为一个突出问题。传统的多叶准直器通常最大叶片速度为3 - 4厘米/秒,最大叶片加速度为50 - 70厘米/秒,这不足以跟踪快速的目标运动。为解决这个问题,我们最近开发了一种高速多叶准直器(HS - MLC)原型,它采用线性电机而非旋转电机来驱动叶片。因此,它继承了线性电机的各种优点,包括直接驱动和高动态性能。本文的主要目的是介绍高速多叶准直器的开发和性能评估。评估包括基本剂量学特性的蒙特卡罗模拟、基于相机的机械性能测量以及针对25组患者测量的运动数据的跟踪实验。蒙特卡罗模拟结果表明,6兆伏时的最大漏射率为1.29%,平均为0.61%。5厘米偏移时的端到端漏射率为3.96%,10厘米偏移时为1.75%。对于标准的10×10厘米射野,在叶片运动的整个范围内,半值层范围为4.8毫米至5.4毫米。机械性能测量表明,最大叶片速度为40厘米/秒,最大叶片加速度为1000厘米/秒,几何精度可保持在0.5毫米以内。关于针对各种运动模式(快速呼吸、不规则呼吸等)的跟踪实验,均方根误差(RMSE)小于0.19毫米。总之,由于其优越的机械性能,高速多叶准直器能够很好地跟踪传统多叶准直器无法胜任的快速目标运动。这种新的多叶准直器设计为实现高精度和高效率的运动管理提供了一种可行的解决方案。