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改善阴道脱垂修复网片手术效果的新策略——最新进展

New strategies to improve results of mesh surgeries for vaginal prolapses repair--an update.

作者信息

Dias Fernando Goulart Fernandes, Dias Paulo Henrique Goulart Fernandes, Prudente Alessandro, Riccetto Cassio

机构信息

Departamento de Urologia da Universidade de Campinas, Campinas, SP, Brasil.

Departamento de Urologia - Universidade Federal do Paraná, Maringá, PR, Brasil.

出版信息

Int Braz J Urol. 2015 Jul-Aug;41(4):623-34. doi: 10.1590/S1677-5538.IBJU.2014.0163.

DOI:10.1590/S1677-5538.IBJU.2014.0163
PMID:26401853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4756989/
Abstract

The use of meshes has become the first option for the treatment of soft tissue disorders as hernias and stress urinary incontinence and widely used in vaginal prolapse's treatment. However, complications related to mesh issues cannot be neglected. Various strategies have been used to improve tissue integration of prosthetic meshes and reduce related complications. The aim of this review is to present the state of art of mesh innovations, presenting the whole arsenal which has been studied worldwide since composite meshes, coated meshes, collagen's derived meshes and tissue engineered prostheses, with focus on its biocompatibility and technical innovations, especially for vaginal prolapse surgery.

摘要

使用补片已成为治疗疝气和压力性尿失禁等软组织疾病的首选方法,并广泛应用于阴道脱垂的治疗。然而,与补片相关的并发症不容忽视。人们已采用各种策略来改善人工补片的组织整合并减少相关并发症。本综述的目的是介绍补片创新的最新进展,展示自复合补片、涂层补片、胶原蛋白衍生补片和组织工程假体以来在全球范围内研究的所有手段,重点关注其生物相容性和技术创新,特别是针对阴道脱垂手术的创新。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa69/4756989/fa221187981e/1677-5538-ibju-41-4-0623-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa69/4756989/9a15707c8412/1677-5538-ibju-41-4-0623-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa69/4756989/fa221187981e/1677-5538-ibju-41-4-0623-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa69/4756989/9a15707c8412/1677-5538-ibju-41-4-0623-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa69/4756989/fa221187981e/1677-5538-ibju-41-4-0623-gf02.jpg

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本文引用的文献

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Systematic review and classification of complications after anterior, posterior, apical, and total vaginal mesh implantation for prolapse repair.阴道前壁、后壁、顶端及全盆底网状物植入治疗盆腔器官脱垂术后并发症的系统评价与分类
Surg Technol Int. 2014 Mar;24:217-24.
2
May polyester with collagen coating mesh decrease the rate of intraperitoneal adhesions in incisional hernia repair?带有胶原蛋白涂层的聚酯网片能否降低切口疝修补术中腹膜粘连的发生率?
Arq Bras Cir Dig. 2013 Jan-Mar;26(1):13-7. doi: 10.1590/s0102-67202013000100004.
3
Highly purified collagen coating enhances tissue adherence and integration properties of monofilament polypropylene meshes.
高度纯化的胶原蛋白涂层可增强单丝聚丙烯网片的组织粘附和整合特性。
Int Urogynecol J. 2013 Oct;24(10):1747-54. doi: 10.1007/s00192-013-2109-8. Epub 2013 May 4.
4
Impregnation of implantable polypropylene mesh with S-nitrosoglutathione-loaded poly(vinyl alcohol).载 S-亚硝基谷胱甘肽的聚(乙烯醇)浸渍可植入性聚丙烯网。
Colloids Surf B Biointerfaces. 2013 Aug 1;108:178-84. doi: 10.1016/j.colsurfb.2013.02.018. Epub 2013 Feb 27.
5
Tissue engineering as a potential alternative or adjunct to surgical reconstruction in treating pelvic organ prolapse.组织工程作为治疗盆腔器官脱垂手术重建的一种潜在替代方法或辅助手段。
Int Urogynecol J. 2013 May;24(5):741-7. doi: 10.1007/s00192-012-1927-4. Epub 2012 Sep 1.
6
Post-implantation alterations of polypropylene in the human.人体中聚丙烯的植入后改变。
J Urol. 2012 Jul;188(1):27-32. doi: 10.1016/j.juro.2012.02.2559. Epub 2012 May 12.
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Int Urogynecol J. 2012 Jun;23(6):669-79. doi: 10.1007/s00192-012-1718-y. Epub 2012 Mar 20.
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Time to rethink: an evidence-based response from pelvic surgeons to the FDA Safety Communication: "UPDATE on Serious Complications Associated with Transvaginal Placement of Surgical Mesh for Pelvic Organ Prolapse".是时候重新思考了:盆腔外科医生对美国食品药品监督管理局安全通告《盆腔器官脱垂经阴道植入手术网片相关严重并发症最新情况》的循证回应
Int Urogynecol J. 2012 Jan;23(1):5-9. doi: 10.1007/s00192-011-1581-2. Epub 2011 Nov 16.
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Beneficial effects of hydrocortisone or spironolactone coating on foreign body response to mesh biomaterial in a mouse model.水皮质醇或螺内酯涂层对鼠模型中生物网材料异物反应的有益作用。
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