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己酮可可碱治疗阴茎异常勃起

Partial Priapism Treated with Pentoxifylline.

作者信息

Cooper Meghan A, Carrion Rafael E, Yang Christopher

机构信息

Lake Erie College of Osteopathic Medicine, Bradenton, Florida, USA.

Department of Urology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.

出版信息

Int Braz J Urol. 2015 Jul-Aug;41(4):804-7. doi: 10.1590/S1677-5538.IBJU.2014.0363.

Abstract

A 26-year-old man suffering from partial priapism was successfully treated with a regimen including pentoxifylline, a nonspecific phosphodiesterase inhibitor that is often used to conservatively treat Peyronie's disease. CASE HYPOTHESIS: Partial priapism is an extremely rare urological condition that is characterized by thrombosis within the proximal segment of a single corpus cavernosum. There have only been 36 reported cases to date. Although several factors have been associated with this unusual disorder, such as trauma or bicycle riding, the etiology is still not completely understood. Treatment is usually conservative and consists of a non-steroidal anti-inflammatory and anti-thrombotic. Promising future implications: This case report supports the utilization of pentoxifylline in patients with partial priapism due to its anti-fibrogenic and anti-thrombotic properties.

摘要

一名患有部分性阴茎异常勃起的26岁男性,采用包括己酮可可碱(一种常用于保守治疗佩罗尼氏病的非特异性磷酸二酯酶抑制剂)的治疗方案成功治愈。病例假设:部分性阴茎异常勃起是一种极其罕见的泌尿系统疾病,其特征是单个海绵体近端段内血栓形成。迄今为止,仅有36例报道病例。尽管有多种因素与这种罕见病症相关,如外伤或骑自行车,但病因仍未完全明确。治疗通常采用保守疗法,包括使用非甾体抗炎药和抗血栓药。未来展望:本病例报告支持在部分性阴茎异常勃起患者中使用己酮可可碱,因其具有抗纤维化和抗血栓特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b1f/4757011/37b10445ed09/1677-5538-ibju-41-4-0804-gf01.jpg

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