Pistollato Francesca, Cano Sandra Sumalla, Elio Iñaki, Vergara Manuel Masias, Giampieri Francesca, Battino Maurizio
Centre for Nutrition and Health, Universidad Europea del Atlántico (UEA), Santander, Spain.
Universidad Internacional Iberoamericana (UNINI), Campeche, Mexico.
J Alzheimers Dis. 2015;48(2):303-18. doi: 10.3233/JAD-150301.
In the last decade, specific dietary patterns, mainly characterized by high consumption of vegetables and fruits, have been proven beneficial for the prevention of both metabolic syndrome (MetS)-related dysfunctions and neurodegenerative disorders, such as Alzheimer's disease (AD). Nowadays, neuroimaging readouts can be used to diagnose AD, investigate MetS effects on brain functionality and anatomy, and assess the effects of dietary supplementations and nutritional patterns in relation to neurodegeneration and AD-related features. Here we review scientific literature describing the use of the most recent neuroimaging techniques to detect AD- and MetS-related brain features, and also to investigate associations between consolidated dietary patterns or nutritional interventions and AD, specifically focusing on observational and intervention studies in humans.
在过去十年中，以大量食用蔬菜和水果为主要特征的特定饮食模式已被证明对预防代谢综合征（MetS）相关功能障碍和神经退行性疾病（如阿尔茨海默病（AD））有益。如今，神经影像学读数可用于诊断AD、研究MetS对脑功能和解剖结构的影响，以及评估饮食补充剂和营养模式对神经退行性变和AD相关特征的影响。在此，我们回顾科学文献，这些文献描述了使用最新神经影像学技术来检测与AD和MetS相关的脑特征，以及研究传统饮食模式或营养干预与AD之间的关联，特别关注针对人类的观察性和干预性研究。
