Maurich V, Collino F, Zacchigna M, Moneghini M
Istituto di Tecnica Farmaceutica, Università degli Studi, Trieste.
Boll Chim Farm. 1989 Dec;128(12):365-9.
A simple, specific and sensitive high-performance liquid chromatographic method for the determination of p-amino benzoic acid (PABA) as impurity in procaine and procainamide hydrochlorides has been developed. The compounds were chromatographed on reversed phase C-18 using water-methanol-acetonitrile solvent system containing sodium lauryl sulphate ion-pair reagent.
