Taghipour-Farshi Hamed, Frounchi Javad, Ahmadiasl Nasser, Shahabi Parviz, Salekzamani Yaghoub
Department of Electrical and Computer Engineering, Tabriz University, Tabriz, Iran.
Department of Neurosciences, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Biomed Mater Eng. 2015;25(3):237-48. doi: 10.3233/BME-151281.
Cuff electrodes have been widely used chronically in different clinical applications. Advancements have been made in selective stimulation by using multi-contact cuff electrodes. Steering anodic current is a strategy to increase selectivity by reshaping and localizing electric fields. There are two configurations for contacts to be implemented in cuff, monopolar and tripolar. A cuff electrode with tripolar configuration can restrict the activation to a more localized region within a nerve trunk compared to a cuff with monopolar configuration and improve the selectivity. Anode contacts in tripolar configuration can be made in two structures, "ring" and "dot".
In this study, the stimulation capabilities of these two structures were evaluated.
The recruitment properties and the selectivity of stimulation were examined by measuring the electric potential produced by stimulation currents.
The results of the present study indicated that using dot configuration, the current needed to stimulate fascicles in tripolar topologies would be reduced by 10%. It was also shown that stimulation threshold was increased by moving anode contacts inward the cuff. On the other hand, stimulation threshold was decreased by moving the anode contacts outward the cuff which would decrease selectivity, too.
We conclude that dot configuration is a better choice for stimulation. Also, a cuff inward placement of 10% relative to the cuff length was near optimal.
袖套电极已在不同临床应用中被广泛长期使用。通过使用多触点袖套电极,在选择性刺激方面取得了进展。引导阳极电流是一种通过重塑和定位电场来提高选择性的策略。袖套中触点的实现有两种配置,单极和三极。与单极配置的袖套相比,三极配置的袖套电极可以将激活限制在神经干内更局部的区域,并提高选择性。三极配置的阳极触点可以制成两种结构,“环形”和“点状”。
在本研究中,评估了这两种结构的刺激能力。
通过测量刺激电流产生的电势来检查募集特性和刺激的选择性。
本研究结果表明,使用点状配置时,三极拓扑结构中刺激束状肌所需的电流将减少10%。还表明,将阳极触点向袖套内移动会提高刺激阈值。另一方面,将阳极触点向袖套外移动会降低刺激阈值,这也会降低选择性。
我们得出结论,点状配置是更好的刺激选择。此外,相对于袖套长度向内放置10%的袖套接近最佳状态。