Slater Lee J, Eftimie Liviu F, Herford Alan S
Private Practice, Scripps Oral Pathology Service, San Diego, CA.
Private Practice, Riverside Oral and Maxillofacial Surgery, Riverside, CA.
J Oral Maxillofac Surg. 2016 Mar;74(3):547-51. doi: 10.1016/j.joms.2015.08.019. Epub 2015 Sep 18.
Primordial odontogenic tumor (POT) was first described in 2014. It typically presents in the posterior mandible of a child or adolescent as a "dentigerous cyst-like" well-circumscribed radiolucency associated with an unerupted molar. POT consists of an ellipsoidal mass of dental papilla-like myxoid connective tissue entirely enveloped in a delicate membrane of ameloblastic epithelium. It shows features of a developing tooth with a huge dental papilla, and because it is devoid of dental hard tissue, it could be regarded a soft tissue odontoma. The lesion histologically mimics early (primordial) stages of tooth development. This report describes a case of POT and POT-like proliferations in an unrelated complex odontoma.
原始牙源性肿瘤(POT)于2014年首次被描述。它通常表现为儿童或青少年下颌后部的一个“含牙囊肿样”边界清晰的透射区,与一颗未萌出的磨牙相关。POT由椭圆形的牙乳头样黏液性结缔组织团块组成,完全被成釉细胞上皮的一层薄膜包裹。它呈现出发育中牙齿的特征,有一个巨大的牙乳头,并且由于缺乏牙硬组织,可被视为软组织牙瘤。该病变在组织学上模仿牙齿发育的早期(原始)阶段。本报告描述了一例POT以及在一个不相关的复杂牙瘤中出现的POT样增殖病例。