四只幼犬的混合性牙源性肿瘤：成釉细胞纤维瘤和成釉细胞纤维牙瘤。
Mixed odontogenic tumors in four young dogs: ameloblastic fibroma and ameloblastic fibro-odontoma.
作者信息
Huang Patrick, Bell Cynthia, Wallace Vanessa, Murphy Brian G
机构信息
Department of Pathology, Microbiology & Immunology, School of Veterinary Medicine, University of California-Davis, Davis, CA (Huang, Murphy).
Department of Diagnostic Medicine and Pathobiology, KS Veterinary Diagnostic Laboratory, Kansas State University, Manhattan, KS (Bell).
出版信息
J Vet Diagn Invest. 2019 Jan;31(1):98-102. doi: 10.1177/1040638718812936. Epub 2018 Nov 18.
Ameloblastic fibroma (AF) and ameloblastic fibro-odontoma (AFO) are mixed odontogenic tumors (odontogenic tumors with induction) that are reported only rarely in dogs. These tumors are histologically complex and, to a degree, recapitulate the early stages of tooth development, comprising 2 types of tissue: neoplastic odontogenic epithelium, and induced ectomesenchyme (dental pulp). AFOs are distinguished from AFs by the additional presence of hard dental matrices such as dentin. Herein, we describe the key diagnostic features of AF and AFO in 4 young dogs.
成釉细胞纤维瘤（AF）和成釉细胞纤维牙瘤（AFO）是混合性牙源性肿瘤（诱导性牙源性肿瘤），在犬类中仅有罕见报道。这些肿瘤在组织学上较为复杂，在一定程度上重现了牙齿发育的早期阶段，由两种组织构成：肿瘤性牙源性上皮和诱导性外胚间充质（牙髓）。AFO与AF的区别在于还存在牙本质等硬牙基质。在此，我们描述了4只幼犬中AF和AFO的关键诊断特征。
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