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[S抗原自身抗体水平的变化及其与色素性视网膜炎(常染色体隐性遗传形式)发展的关系]

[Variations in the level of S antigen auto-antibodies and their relation to the development of retinitis pigmentosa (autosomal recessive genetic form)].

作者信息

Heredia Garcia C D, Garcia Calderon P A

出版信息

Ophtalmologie. 1989 Sep-Dec;3(4):273-4.

PMID:2641133
Abstract

A group of 40 patients with retinitis pigmentosa (autosomal recessive) were studied. The levels of soluble retinal antigen (S antigen of human origin) auto-antibodies were measured by means of the enzyme-linked-immunosorbent assay. The results obtained were compared with those of a control population of 100 healthy subjects (p less than 0.001). A statistically significant correlation (r = 0.451, p less than 0.01) was observed when comparison was made between the anti-S levels and the time elapsed from the moment of retinitis pigmentosa diagnosis.

摘要

对40例(常染色体隐性遗传)色素性视网膜炎患者进行了研究。采用酶联免疫吸附测定法测量可溶性视网膜抗原(人源S抗原)自身抗体水平。将所得结果与100名健康受试者的对照群体结果进行比较(p<0.001)。在比较抗S水平与色素性视网膜炎诊断时刻起经过的时间时,观察到具有统计学意义的相关性(r = 0.451,p<0.01)。

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