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开放急诊手术在急性肠系膜缺血治疗中的重要性。

The importance of open emergency surgery in the treatment of acute mesenteric ischemia.

作者信息

Duran Mansur, Pohl E, Grabitz K, Schelzig H, Sagban T A, Simon F

机构信息

Clinic for Vascular- and Endovascular Surgery, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany.

出版信息

World J Emerg Surg. 2015 Sep 26;10:45. doi: 10.1186/s13017-015-0041-6. eCollection 2015.

Abstract

OBJECTIVE

Acute mesenteric ischemia (AMI) is a complex disease with a high mortality rate. A patient's chance of survival depends on early diagnosis and rapid revascularization to prevent progression of intestinal gangrene. We reviewed our experience with open surgery treatment in 54 cases of AMI.

METHODS

A monocentric retrospective study was conducted between 01/01/2001 and 04/30/2014; 54 AMI patients with a mean age of 56.6 years underwent surgery (26 women and 28 men). Retrospectively, the risk factors, management until diagnosis, vascular therapy and follow-up were evaluated.

RESULTS

The symptom upon admission was an acute abdominal pain event. The delay time from admission to surgery was, on average, 13.9 h (n = 34). The therapeutic procedures were open surgical operations. The complication rate was (53.7 %) (n = 29). The 30-day mortality was 29.6 % (n = 16). The late mortality rate was 24.1 % (n = 13), and the cumulative survival risk was 44.6 %. Survival was, on average, 60.54 months; however, in the over 70-year-old patient subgroup, the survival rate was 9.5 months (p = 0.035). The mortality rate was 27 % (n = 22) in the <12 h delay group, 20 % (n = 5) in the 12-24 h delay group, and 50 % (n = 7) in the > 24 h delay group.

CONCLUSIONS

The form of therapy depends on the intraoperative findings and the type of occlusion. Although the mortality rate has decreased in the last decade, in patients over 70 years of age, a significantly worse prognosis was seen.

摘要

目的

急性肠系膜缺血(AMI)是一种死亡率很高的复杂疾病。患者的生存机会取决于早期诊断和快速血管再通,以防止肠坏疽进展。我们回顾了54例AMI患者的开放手术治疗经验。

方法

在2001年1月1日至2014年4月30日期间进行了一项单中心回顾性研究;54例平均年龄为56.6岁的AMI患者接受了手术(26名女性和28名男性)。回顾性评估危险因素、诊断前的处理、血管治疗及随访情况。

结果

入院时症状为急性腹痛。从入院到手术的平均延迟时间为13.9小时(n = 34)。治疗方法为开放手术。并发症发生率为53.7%(n = 29)。30天死亡率为29.6%(n = 16)。晚期死亡率为24.1%(n = 13),累积生存风险为44.6%。平均生存时间为60.54个月;然而,在70岁以上患者亚组中,生存率为9.5个月(p = 0.035)。延迟时间<12小时组的死亡率为27%(n = 22),12 - 24小时组为20%(n = 5),>24小时组为50%(n = 7)。

结论

治疗方式取决于术中发现及闭塞类型。尽管在过去十年中死亡率有所下降,但在70岁以上患者中,预后明显更差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/142a/4583757/69c7f652048f/13017_2015_41_Fig1_HTML.jpg

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