Janecka I P, Sekhar L N
Center for Cranial Base Surgery, Pittsburgh.
Oncology (Williston Park). 1989 Mar;3(3):69-74; discussion 79-80.
Most cranial base tumors are now treatable by surgery because of recent advances, including the precision of modern diagnostic and interventional radiology. In the past two years, the authors have treated 91 patients with tumors involving the cranial base; over 60% were malignant. Most patients underwent a combined intracranial-extracranial procedure for tumor removal with immediate reconstruction. The complication rate was under 10% and most patients (more than 80%) are tumor-free in follow-up of 2-24 months. While cranial base surgery is now established as a field of surgical oncology, its true benefit to patients with tumors in this location, measured in five and 10-year tumor-free survival, cannot yet be determined.
由于包括现代诊断和介入放射学的精准度在内的近期进展，现在大多数颅底肿瘤都可以通过手术治疗。在过去两年中，作者治疗了91例累及颅底的肿瘤患者；其中超过60%为恶性肿瘤。大多数患者接受了颅内-颅外联合手术以切除肿瘤并立即进行重建。并发症发生率低于10%，并且在2至24个月的随访中，大多数患者（超过80%）无肿瘤。虽然颅底手术现在已成为外科肿瘤学的一个领域，但其对该部位肿瘤患者的真正益处，以五年和十年无瘤生存率来衡量，尚未确定。
