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在肾移植中，何时超声造影比传统超声联合多普勒成像更具优势？

When is contrast-enhanced sonography preferable over conventional ultrasound combined with Doppler imaging in renal transplantation?

作者信息

Zeisbrich Markus, Kihm Lars P, Drüschler Felix, Zeier Martin, Schwenger Vedat

机构信息

Department of Nephrology , University Hospital , Heidelberg , Germany.

出版信息

Clin Kidney J. 2015 Oct;8(5):606-14. doi: 10.1093/ckj/sfv070. Epub 2015 Aug 8.

DOI:10.1093/ckj/sfv070
PMID:26413289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4581388/
Abstract

Conventional ultrasound in combination with colour Doppler imaging is still the standard diagnostic procedure for patients after renal transplantation. However, while conventional ultrasound in combination with Doppler imaging can diagnose renal artery stenosis and vein thrombosis, it is not possible to display subtle microvascular tissue perfusion, which is crucial for the evaluation of acute and chronic allograft dysfunctions. In contrast, real-time contrast-enhanced sonography (CES) uses gas-filled microbubbles not only to visualize but also to quantify renal blood flow and perfusion even in the small renal arterioles and capillaries. It is an easy to perform and non-invasive imaging technique that augments diagnostic capabilities in patients after renal transplantation. Specifically in the postoperative setting, CES has been shown to be superior to conventional ultrasound in combination with Doppler imaging in uncovering even subtle microvascular disturbances in the allograft perfusion. In addition, quantitative perfusion parameters derived from CES show predictive capability regarding long-term kidney function.

摘要

传统超声结合彩色多普勒成像仍是肾移植术后患者的标准诊断方法。然而，虽然传统超声结合多普勒成像可以诊断肾动脉狭窄和静脉血栓形成，但无法显示细微的微血管组织灌注情况，而这对于评估急性和慢性移植肾机能障碍至关重要。相比之下，实时超声造影（CES）使用充气微泡不仅可以可视化，还能量化肾血流和灌注，甚至在小肾动脉和毛细血管中也能做到。它是一种易于操作且无创的成像技术，可增强肾移植术后患者的诊断能力。特别是在术后情况下，CES已被证明在发现移植肾灌注中即使是细微的微血管紊乱方面优于传统超声结合多普勒成像。此外，从CES得出的定量灌注参数显示出对长期肾功能的预测能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/94557a44e8dc/sfv07004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/e9d111339502/sfv07001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/f352eb0a2366/sfv07002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/9b097cea09a4/sfv07003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/94557a44e8dc/sfv07004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/e9d111339502/sfv07001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/f352eb0a2366/sfv07002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/9b097cea09a4/sfv07003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfee/4581388/94557a44e8dc/sfv07004.jpg

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Ann Transplant. 2021 May 4;26:e929729. doi: 10.12659/AOT.929729.
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