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半侧颜面短小畸形下颌骨的三维功能单元分析——初步报告

Three-dimensional functional unit analysis of hemifacial microsomia mandible-a preliminary report.

作者信息

Choi Ji Wook, Kim Byung Hoon, Kim Hyung Soo, Yu Tae Hoon, Kim Bong Chul, Lee Sang-Hwy

机构信息

Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, 50 Yonsei-ro Seodaemun-Gu, Seoul, 120-752 Korea.

Department of Oral and Maxillofacial Surgery, Daejeon Dental Hospital, College of Dentistry, Wonkwang University, Daejeon, Korea.

出版信息

Maxillofac Plast Reconstr Surg. 2015 Sep 16;37(1):28. doi: 10.1186/s40902-015-0027-z. eCollection 2015 Dec.

Abstract

BACKGROUND

The aim of this study was to present three-dimensional (3D) structural characteristics of the mandible in the hemifacial microsomia. The mandible has six distinct functional units, and its architecture is the sum of balanced growth of each functional unit and surrounding matrix.

METHODS

In order to characterize the mandibular 3D architecture of hemifacial microsomia, we analyzed the mandibular functional units of four hemifacial microsomia patients using the 3D reconstructed computed tomography (CT) images. And we compared the functional unit size between affected and non-affected side.

RESULTS

The length of condyle and angle showed significant differences between affected and non-affected sides. However, the length of mandibular body showed insignificant differences. The size differences between affected and non-affected side were observed at the condyle, angle, and body in descending order.

CONCLUSIONS

This preliminary study suggests that the main etiopathogenic units are condyle and angle in the hemifacial microsomia mandible. Further investigation with the increased number of subjects will be helpful to establish treatment modality by etiopathogenic targeting of hemifacial microsomia.

摘要

背景

本研究的目的是呈现半侧颜面短小畸形患者下颌骨的三维(3D)结构特征。下颌骨有六个不同的功能单元,其结构是每个功能单元与周围基质平衡生长的总和。

方法

为了描述半侧颜面短小畸形患者下颌骨的三维结构,我们使用三维重建计算机断层扫描(CT)图像分析了四名半侧颜面短小畸形患者的下颌骨功能单元。并且我们比较了患侧和非患侧的功能单元大小。

结果

髁突长度和下颌角在患侧和非患侧之间存在显著差异。然而,下颌体长差异不显著。患侧和非患侧之间的大小差异在髁突、下颌角和下颌体处依次观察到。

结论

这项初步研究表明,半侧颜面短小畸形下颌骨的主要致病单元是髁突和下颌角。增加研究对象数量的进一步调查将有助于通过针对半侧颜面短小畸形的致病靶点来确立治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeca/5126918/489022240259/40902_2015_27_Fig1_HTML.jpg

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