Alex Saji, Tiwari Ashutosh
J Nanosci Nanotechnol. 2015 Mar;15(3):1869-94. doi: 10.1166/jnn.2015.9718.
The past few decades have witnessed significant advances in the development of functionalized gold nanoparticles for applications in various fields such as chemistry, biology, pharmacy and physics. Although it has been more than 150 years since they were first synthesized, extensive research has recently been undertaken to improve or modify gold nanoparticles, thereby opening up opportunities to enhance and optimize their potential and breadth of their applicability. Recently developed methods have allowed a precise control of gold nanoparticle size and the modification of gold nanoparticles with suitable protecting and functionalizing agents, facilitate their applications in different areas such as chemical and biological sensing, imaging and biomedical applications. This review focuses on the recent developments in various methods for the size and shape controlled synthesis of gold nanoparticles, understanding of different properties of gold nanoparticles and their applications in various fields. Particular attention is given to the chemical and biological sensing applications of gold nanoparticles and on the advances in the controlled ordering of gold nanoparticles for creating nanostructures for diverse applications.
在过去几十年里,功能化金纳米粒子在化学、生物学、药学和物理学等各个领域的应用开发取得了重大进展。尽管自首次合成金纳米粒子以来已有150多年,但最近人们开展了广泛研究以改进或修饰金纳米粒子,从而为增强和优化其潜力及应用广度带来了机遇。最近开发的方法能够精确控制金纳米粒子的尺寸,并使用合适的保护剂和功能化剂对金纳米粒子进行修饰,促进了它们在化学和生物传感、成像及生物医学应用等不同领域的应用。本综述聚焦于金纳米粒子尺寸和形状控制合成的各种方法的最新进展、对金纳米粒子不同性质的理解及其在各个领域的应用。特别关注金纳米粒子的化学和生物传感应用以及金纳米粒子可控有序排列以创建用于各种应用的纳米结构方面的进展。