Department of Biomedical Engineering, Washington University, St. Louis, MO 63130, USA.
Chem Soc Rev. 2011 Jan;40(1):44-56. doi: 10.1039/b821763g. Epub 2010 Sep 6.
Gold nanostructures have proven to be a versatile platform for a broad range of biomedical applications, with potential use in numerous areas including: diagnostics and sensing, in vitro and in vivo imaging, and therapeutic techniques. These applications are possible because of the highly favorable properties of gold nanostructures, many of which can be tailored for specific applications. In the first part of this tutorial review, we will discuss the most critical properties of gold nanostructures for biomedical applications: surface chemistry, localized surface plasmon resonance (LSPR), and morphology. In the second part of the review, we will discuss how these properties can be harnessed for a selection of biomedical applications, aiming to give the reader an overview of general strategies as well as highlight some recent advances in this field.
金纳米结构已被证明是一个多功能的平台，可用于广泛的生物医学应用，具有潜在的应用领域包括：诊断和传感、体外和体内成像以及治疗技术。这些应用之所以成为可能，是因为金纳米结构具有高度优良的特性，其中许多特性可以针对特定应用进行定制。在本教程综述的第一部分，我们将讨论金纳米结构在生物医学应用中最重要的特性：表面化学、局域表面等离子体共振（LSPR）和形态。在综述的第二部分，我们将讨论如何利用这些特性来进行一些生物医学应用，旨在为读者提供一般策略的概述，并强调该领域的一些最新进展。
