Özdek Suat, Kul Mustafa, Barış Akcan Abdullah, Çekmez Ferhat, Aydemir Gökhan, Aydınöz Seçil, Karademir Ferhan, Süleymanoğlu Selami
a Department of Pediatrics , GATA, Haydarpaşa Teaching Hospital , İstanbul , Turkey and.
b Department of Pediatrics, Division of Neonatology , Adnan Menderes University, School of Medicine , Aydın , Turkey.
J Matern Fetal Neonatal Med. 2016;29(15):2434-7. doi: 10.3109/14767058.2015.1086743. Epub 2015 Sep 28.
Jaundice is a problem in newborns. There are many maternal and infant-related factors affecting neonatal jaundice. The maternal pre-pregnancy weight, maternal body mass index (BMI) and gestational weight gain may have an effect on the newborn bilirubin levels. We research the effect of the maternal pre-pregnancy weight and gestational weight gain on the bilirubin levels of the newborn infants in the first 2 weeks prospectively.
Term and healthy infants who were born between 38 and 42 weeks in our clinic were included in the study. Maternal pre-pregnancy BMIs were calculated. Babies were divided into three groups according to their mothers' advised amount of gestational weight gain. Total serum bilirubin (TSB) values of the newborns were measured in the 2nd, 5th and 15th postnatal days.
In our study, the 5th and 15th day capillary bilirubin level of the babies with mothers who gained more weight than the advised amount during pregnancy were found statistically significant higher compared to the other two groups (p < 0.05). Similarly, the hematocrit level of the babies with mothers who gained more weight than the advised amount were found statistically significant higher compared to the other two groups (p < 0.05).
We conclude that the babies with mothers who gained more weight than the advised amount were under risk for newborn jaundice. Therefore, these babies should be monitored more closely for neonatal jaundice and prolonged jaundice.
黄疸是新生儿的一个问题。有许多与母婴相关的因素会影响新生儿黄疸。母亲孕前体重、母亲体重指数(BMI)和孕期体重增加可能会对新生儿胆红素水平产生影响。我们前瞻性地研究母亲孕前体重和孕期体重增加对新生儿出生后前2周胆红素水平的影响。
本研究纳入了在我们诊所出生的38至42周足月健康婴儿。计算母亲孕前BMI。根据母亲建议的孕期体重增加量将婴儿分为三组。在出生后第2天、第5天和第15天测量新生儿的总血清胆红素(TSB)值。
在我们的研究中,发现孕期体重增加超过建议量的母亲所生婴儿在出生后第5天和第15天的毛细血管胆红素水平与其他两组相比有统计学意义的升高(p < 0.05)。同样,孕期体重增加超过建议量的母亲所生婴儿的血细胞比容水平与其他两组相比有统计学意义的升高(p < 0.05)。
我们得出结论,母亲体重增加超过建议量的婴儿有患新生儿黄疸的风险。因此,对于这些婴儿应更密切地监测新生儿黄疸和黄疸持续时间。