Herman R M, Thor P J, Krystyniecki J, Weisbrodt N W
I Department of General Surgery, Copernicus School of Medicine, Cracow.
Acta Physiol Pol. 1989 Mar-Apr;40(2):250-4.
This study was designed to determine the rates of gastric emptying of water, saline and a 20% glucose solution in patients with gastric and duodenal ulcers. In all subjects, gastric emptying was fastest after administration of the saline, slower with water and the slowest with glucose. Significant statistical differences (p less than 0.05) in emptying rates between normal subjects and the group with duodenal ulcer were seen when water and saline but not glucose were used. We conclude that inhibitory effects of the osmotic receptors are not changed in gastric and duodenal ulcer patients. However, the emptying rates were higher when osmotic stimulus was withheld.
本研究旨在测定胃溃疡和十二指肠溃疡患者水、盐水及20%葡萄糖溶液的胃排空率。在所有受试者中，给予盐水后胃排空最快，水次之，葡萄糖最慢。当使用水和盐水而不是葡萄糖时，正常受试者与十二指肠溃疡组之间的排空率存在显著统计学差异（p<0.05）。我们得出结论，胃和十二指肠溃疡患者中渗透感受器的抑制作用没有改变。然而，当不给予渗透刺激时，排空率更高。
